TB-Profiler result

Run: SRR1723992

Summary

Run ID: SRR1723992

Sample name:

Date: 18-08-2022 08:14:41

Number of reads: 4929344

Percentage reads mapped: 99.13

Strain: lineage4.4.2

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 1.0
lineage4.4.2 Euro-American T1;T2 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5302 p.Glu21Asp missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 767314 p.Tyr1315* stop_gained 0.35
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1417236 p.Val38Met missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154177 c.1935G>A synonymous_variant 0.99
ald 3086788 c.-32T>C upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243991 c.759T>G synonymous_variant 1.0
embA 4245946 p.Ile905Thr missense_variant 1.0
embB 4246508 c.-6G>A upstream_gene_variant 0.98
ubiA 4268928 c.906C>T synonymous_variant 1.0
ubiA 4269375 c.459G>A synonymous_variant 0.99