TB-Profiler result

Run: SRR18213665
Summary

Run ID: SRR18213665

Sample name:

Date: 03-04-2023 19:24:18

Number of reads: 3975592

Percentage reads mapped: 99.64

Strain: lineage4.6

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.22
rpoB 759620 c.-187A>C upstream_gene_variant 0.16
rpoC 763644 p.Met92Thr missense_variant 0.99
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777427 p.Thr352Pro missense_variant 0.15
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.15
fbiC 1304159 p.Val410Gly missense_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674952 p.Pro251Ala missense_variant 0.18
inhA 1674966 c.765T>G synonymous_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155532 p.Asp194Asn missense_variant 0.99
PPE35 2168080 p.Thr845Ala missense_variant 1.0
PPE35 2169866 c.747G>C synonymous_variant 0.12
PPE35 2170198 p.Ala139Thr missense_variant 0.99
PPE35 2170792 c.-180T>C upstream_gene_variant 0.96
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.32
ahpC 2726341 p.Val50Gly missense_variant 0.27
pepQ 2859904 p.Val172Gly missense_variant 0.19
ribD 2986651 c.-188G>A upstream_gene_variant 0.97
ribD 2987307 p.Ala157Pro missense_variant 0.12
ribD 2987323 p.Val162Gly missense_variant 0.23
thyA 3073806 c.666C>G synonymous_variant 0.15
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038857 c.1848C>A synonymous_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0