TB-Profiler result

Run: SRR19428544

Summary

Run ID: SRR19428544

Sample name:

Date: 03-04-2023 21:39:55

Number of reads: 1782491

Percentage reads mapped: 99.72

Strain:

Drug-resistance: Sensitive


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3.4.2 Euro-American (LAM) LAM1;LAM4;LAM11 RD174 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6140 p.Val301Leu missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575551 p.Met68Ile missense_variant 0.25
mshA 575750 p.Gly135Trp missense_variant 0.25
mshA 575906 p.Ala187Thr missense_variant 0.33
mshA 575923 p.Asp192Glu missense_variant 0.33
rpoB 761537 c.1731C>A synonymous_variant 0.12
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801231 c.423C>A synonymous_variant 0.12
fbiC 1304066 p.Ala379Glu missense_variant 0.5
fbiC 1305419 p.Val830Ala missense_variant 0.17
Rv1258c 1406088 p.Ala418Asp missense_variant 0.15
Rv1258c 1407521 c.-181C>T upstream_gene_variant 0.2
embR 1416195 p.His385Tyr missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1834925 p.Gly462* stop_gained 0.12
tlyA 1918287 c.348C>A synonymous_variant 0.33
ndh 2102169 p.Gln292Lys missense_variant 0.29
ndh 2102304 p.Ala247Ser missense_variant 0.17
katG 2155720 p.Pro131Gln missense_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747214 p.Pro129Thr missense_variant 0.13
pepQ 2859987 c.432A>T synonymous_variant 0.67
pepQ 2860601 c.-183C>T upstream_gene_variant 1.0
ribD 2987285 c.447C>A synonymous_variant 0.14
Rv2752c 3066270 c.-80delA upstream_gene_variant 0.11
Rv2752c 3066287 c.-96G>C upstream_gene_variant 0.18
thyX 3067208 p.Leu246Phe missense_variant 0.5
thyX 3067845 p.Ala34Glu missense_variant 0.15
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087355 p.Ala179Gly missense_variant 0.13
fbiD 3338975 c.-143C>A upstream_gene_variant 0.17
fbiD 3339004 c.-114A>G upstream_gene_variant 0.14
fbiD 3339176 p.Ala20Val missense_variant 0.25
fbiD 3339332 p.Ala72Glu missense_variant 1.0
Rv3083 3449118 c.615G>T synonymous_variant 0.2
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474877 p.Arg291Gly missense_variant 0.2
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
Rv3236c 3612132 p.Ala329Ser missense_variant 0.12
fbiA 3641222 p.Pro227His missense_variant 0.17
fbiB 3641238 c.-297G>T upstream_gene_variant 0.15
fbiA 3641293 p.Pro251Thr missense_variant 0.12
fbiA 3641486 p.Ala315Glu missense_variant 0.17
fbiA 3641503 p.Arg321Ser missense_variant 0.17
fbiB 3641546 c.12C>A synonymous_variant 0.17
fbiB 3641582 c.48C>A synonymous_variant 0.29
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embC 4241484 p.Val541Ala missense_variant 0.13
embC 4242152 p.Gly764Cys missense_variant 0.12
embC 4242248 p.Ala796Thr missense_variant 0.33
embC 4242702 p.Ala947Val missense_variant 1.0
embA 4243756 p.Thr175Asn missense_variant 0.17
embA 4245432 p.Ala734Thr missense_variant 0.15
embA 4245919 p.Trp896Leu missense_variant 0.29
embB 4246566 p.Gly18Val missense_variant 0.25
embB 4246829 p.Gly106Cys missense_variant 0.17
embB 4246938 p.Ser142Tyr missense_variant 0.15
embB 4247009 p.Asp166Asn missense_variant 0.33
embB 4247792 c.1279C>A synonymous_variant 0.17
embB 4247918 p.Arg469Gly missense_variant 0.18
embB 4249252 c.2739C>A synonymous_variant 0.18
aftB 4267620 p.Gly406Asp missense_variant 0.14
aftB 4267622 c.1215G>T synonymous_variant 0.15
aftB 4268505 p.Arg111Leu missense_variant 0.12
aftB 4268512 c.324delC frameshift_variant 0.12
aftB 4268867 c.-31G>T upstream_gene_variant 0.17
ethA 4328019 c.-546G>A upstream_gene_variant 1.0
ethA 4328058 c.-585T>C upstream_gene_variant 0.12
ethA 4328452 c.-979C>A upstream_gene_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0
gid 4408216 c.-14C>A upstream_gene_variant 0.2