TB-Profiler result

Run: SRR20969966
Summary

Run ID: SRR20969966

Sample name:

Date: 13-03-2023 17:29:39

Number of reads: 9401574

Percentage reads mapped: 99.59

Strain: lineage4.5;lineage4.4.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 0.88
lineage4.4 Euro-American S;T None 0.13
lineage4.4.2 Euro-American T1;T2 None 0.16
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 0.91
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 0.86
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777353 c.1128G>A synonymous_variant 0.89
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674090 c.-112C>T upstream_gene_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170568 p.Ile15Met missense_variant 0.88
Rv1979c 2221856 p.Ile437Leu missense_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290077 c.-836G>T upstream_gene_variant 0.89
Rv2752c 3065256 p.Met312Ile missense_variant 0.14
Rv2752c 3066099 p.Met31Ile missense_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 0.13
fprA 3473996 c.-10_-9insA upstream_gene_variant 1.0
rpoA 3878575 c.-68C>T upstream_gene_variant 0.91
clpC1 4038318 p.Pro796Leu missense_variant 0.87
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246508 c.-6G>A upstream_gene_variant 0.13
aftB 4268928 c.-92C>T upstream_gene_variant 0.12
aftB 4269375 c.-539G>A upstream_gene_variant 0.15
whiB6 4338595 c.-75delG upstream_gene_variant 1.0