TB-Profiler result

Run: SRR2101800
Summary

Run ID: SRR2101800

Sample name:

Date: 03-04-2023 23:55:21

Number of reads: 687717

Percentage reads mapped: 99.29

Strain: lineage4.4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 0.99
lineage4.4.1 Euro-American (S-type) S;T None 0.98
lineage4.4.1.1 Euro-American S;Orphans None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9138 p.Gln613Glu missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576713 c.1368_1369delCG frameshift_variant 0.1
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777416 c.1065G>T synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406964 p.Ser126* stop_gained 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2168479 p.Thr712Pro missense_variant 1.0
PPE35 2169840 p.Gly258Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288895 c.338_346delGCACGCCAC disruptive_inframe_deletion 0.29
Rv2752c 3066104 p.Asn30Asp missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3338999 c.-119T>C upstream_gene_variant 0.1
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568779 c.-100T>C upstream_gene_variant 0.95
Rv3236c 3612455 p.Arg221Leu missense_variant 0.11
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
fbiB 3642216 p.Thr228Ala missense_variant 0.12
embC 4240576 c.714A>G synonymous_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249009 c.2496G>A synonymous_variant 0.16
embB 4249126 c.2613G>A synonymous_variant 0.11
aftB 4267471 p.Asn456Tyr missense_variant 0.13
aftB 4267924 p.Val305Leu missense_variant 0.25
aftB 4268248 c.589C>T synonymous_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0