TB-Profiler result

Run: SRR21595948
Summary

Run ID: SRR21595948

Sample name:

Date: 04-04-2023 02:17:17

Number of reads: 558767

Percentage reads mapped: 94.94

Strain: lineage4.1.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
ccsA 619807 c.-84G>T upstream_gene_variant 0.11
ccsA 620562 c.672C>A synonymous_variant 0.12
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.4
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.33
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 0.33
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.33
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.33
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.33
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.33
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.33
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.33
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.33
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.33
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.5
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.5
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.5
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.5
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.67
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.67
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.67
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.67
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.5
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.5
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.5
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.67
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.67
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 1.0
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 1.0
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.5
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.5
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.5
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.5
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.5
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.5
rrs 1472596 n.751G>T non_coding_transcript_exon_variant 0.4
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.4
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 0.4
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.4
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.5
rrs 1473149 n.1304G>A non_coding_transcript_exon_variant 0.4
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.33
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.33
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.33
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.33
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.33
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.33
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.33
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.4
rrs 1473281 n.1436C>A non_coding_transcript_exon_variant 0.4
rrs 1473282 n.1437C>G non_coding_transcript_exon_variant 0.4
rrs 1473288 n.1443C>A non_coding_transcript_exon_variant 0.5
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.5
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.5
rrs 1473296 n.1451G>C non_coding_transcript_exon_variant 0.4
rrs 1473297 n.1452G>T non_coding_transcript_exon_variant 0.4
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.4
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.4
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.4
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.4
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.5
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.67
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.5
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.67
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.5
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.5
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.5
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.5
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.4
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.4
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.4
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.4
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.4
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.4
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.4
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.5
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.5
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.5
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.5
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.56
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.6
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.56
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.5
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.5
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.5
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.5
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.57
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.57
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.57
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.78
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.78
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.83
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.8
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.8
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.8
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.8
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.8
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.8
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.8
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.8
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.8
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.8
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.8
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 1.0
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 1.0
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 1.0
inhA 1674971 p.Ile257Thr missense_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102227 c.816C>A synonymous_variant 0.11
PPE35 2168468 c.2145C>T synonymous_variant 0.15
Rv1979c 2222796 c.369C>T synonymous_variant 0.13
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
eis 2714559 c.774C>T synonymous_variant 0.14
ahpC 2726245 p.Leu18Pro missense_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568428 c.252A>G synonymous_variant 0.22
rpoA 3878185 p.Gly108Val missense_variant 1.0
clpC1 4040621 c.84C>T synonymous_variant 0.11
embC 4239876 p.Ala5Asp missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4246529 p.Ser6Arg missense_variant 0.29
embB 4246584 p.Arg24Pro missense_variant 0.67
embB 4247028 p.Leu172Arg missense_variant 0.22
embB 4248319 c.1806A>T synonymous_variant 0.18
embB 4248324 p.Ala604Gly missense_variant 0.21
ethR 4328024 p.Arg159Gln missense_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0