TB-Profiler result

Run: SRR22528559
Summary

Run ID: SRR22528559

Sample name:

Date: 04-04-2023 04:18:45

Number of reads: 857511

Percentage reads mapped: 99.6

Strain: lineage4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6052 p.Ile271Met missense_variant 1.0
gyrA 6487 c.-815C>G upstream_gene_variant 1.0
gyrB 7134 p.Val632Ala missense_variant 0.12
gyrB 7221 p.Ser661Thr missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620773 p.Ile295Val missense_variant 0.11
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 765814 c.2445A>G synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776756 c.1725C>T synonymous_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416699 p.Leu217Val missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476570 n.2913A>G non_coding_transcript_exon_variant 0.14
inhA 1673865 c.-337C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168272 p.Leu781Met missense_variant 0.18
PPE35 2169428 c.1184delG frameshift_variant 0.17
PPE35 2170495 p.Ser40Thr missense_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290034 c.-793C>T upstream_gene_variant 0.14
Rv2752c 3064546 p.Pro549Arg missense_variant 0.11
thyX 3067558 p.His130Tyr missense_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878630 c.-123G>C upstream_gene_variant 0.17
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4246670 p.Thr53Pro missense_variant 0.1
embB 4249408 c.2895G>A synonymous_variant 1.0
aftB 4267186 p.Pro551Ser missense_variant 0.13
ubiA 4269538 p.Glu99Gly missense_variant 0.11
ethA 4326025 c.1449G>A synonymous_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0