Run ID: SRR5485574
Sample name:
Date: 18-08-2022 08:25:08
Number of reads: 135590
Percentage reads mapped: 99.15
Strain:
Drug-resistance: MDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761155 | p.Ser450Leu | missense_variant | 1.0 | rifampicin |
fabG1 | 1673425 | c.-15C>T | upstream_gene_variant | 1.0 | isoniazid, ethionamide |
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid |
pncA | 2289231 | p.Leu4Trp | missense_variant | 1.0 | pyrazinamide |
embB | 4247429 | p.Met306Val | missense_variant | 1.0 | ethambutol |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7662 | p.Asn121Asp | missense_variant | 0.14 |
gyrA | 7665 | p.Asp122Asn | missense_variant | 0.14 |
rpoB | 761226 | p.Tyr474Glu | missense_variant | 0.17 |
rpsL | 781661 | p.Cys34Trp | missense_variant | 0.18 |
rrs | 1472493 | n.648T>G | non_coding_transcript_exon_variant | 0.27 |
rrs | 1473249 | n.1404T>C | non_coding_transcript_exon_variant | 0.15 |
fabG1 | 1673412 | c.-27G>A | upstream_gene_variant | 0.15 |
embB | 4247616 | p.Glu368Gly | missense_variant | 0.25 |