TB-Profiler result

Run: SRR6045920
Summary

Run ID: SRR6045920

Sample name:

Date: 04-04-2023 12:07:53

Number of reads: 2518960

Percentage reads mapped: 97.04

Strain: lineage4.1.1

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.24 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.33
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.17
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.17
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.2
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.71
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.71
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.71
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.7
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.73
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.67
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.67
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.12
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.62
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.59
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.44
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.4
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.56
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.1
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.5
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.5
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.35
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.25
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.25
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.2
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.25
rrs 1472673 n.828T>A non_coding_transcript_exon_variant 0.25
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.29
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.29
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.25
rrs 1472687 n.843dupT non_coding_transcript_exon_variant 0.25
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.25
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.29
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.27
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.27
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.22
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.21
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.12
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.1
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.11
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.11
rrs 1472990 n.1145A>T non_coding_transcript_exon_variant 0.12
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.14
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.14
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.15
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.15
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.33
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.27
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 0.33
rrl 1473832 n.175C>A non_coding_transcript_exon_variant 0.25
rrl 1473833 n.176G>T non_coding_transcript_exon_variant 0.25
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 0.22
rrl 1474161 n.504A>G non_coding_transcript_exon_variant 0.25
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.25
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.25
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.27
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.27
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.27
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.46
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.46
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.46
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.55
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.46
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.36
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.4
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.33
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.33
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.31
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.23
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.29
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.31
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.31
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.31
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.38
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.38
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.64
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.58
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.4
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.4
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.4
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.36
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.25
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.35
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.31
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.15
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.5
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155617 c.495T>C synonymous_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.19
PPE35 2170053 p.Thr187Ser missense_variant 0.19
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518147 c.33C>T synonymous_variant 0.24
kasA 2519057 p.Thr315Ser missense_variant 0.12
kasA 2519062 c.948T>G synonymous_variant 0.12
ahpC 2726338 p.Val49Gly missense_variant 0.21
thyA 3074220 c.252A>T synonymous_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3641447 p.Thr302Met missense_variant 0.99
rpoA 3877553 p.Glu319Lys missense_variant 1.0
embC 4240897 c.1035C>G synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
ethR 4327303 c.-246G>A upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0