TB-Profiler result

Run: SRR6257012
Summary

Run ID: SRR6257012

Sample name:

Date: 04-04-2023 13:22:48

Number of reads: 510939

Percentage reads mapped: 100.0

Strain: lineage4.8

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 0.94
ccsA 619942 p.Phe18Leu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 778064 c.-926G>C upstream_gene_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.91
rrl 1475089 n.1432A>G non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918339 p.Thr134Ser missense_variant 0.13
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289960 c.-719C>T upstream_gene_variant 0.12
folC 2746540 c.1059G>A synonymous_variant 0.11
folC 2746949 p.Ala217Val missense_variant 0.12
ald 3087549 p.Ala244Thr missense_variant 0.11
fbiD 3339203 p.Val29Ala missense_variant 0.15
Rv3083 3448475 c.-29T>G upstream_gene_variant 0.22
Rv3236c 3612600 p.Ala173Ser missense_variant 0.1
clpC1 4038230 p.Lys825Asn missense_variant 0.1
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246718 c.209delC frameshift_variant 0.14
embB 4247395 c.882C>T synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0