TB-Profiler result

Run: SRR6785340
Summary

Run ID: SRR6785340

Sample name:

Date: 04-04-2023 15:47:53

Number of reads: 1541521

Percentage reads mapped: 99.55

Strain: lineage4.2.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.1 Euro-American (TUR) H3;H4 None 1.0
lineage4.2.1.1 Euro-American (TUR) H3;H4 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6936 p.Pro566Gln missense_variant 0.17
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 762514 p.Asp903Ala missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777451 p.Val344Leu missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673380 c.-60C>G upstream_gene_variant 0.38
rpsA 1834518 p.Leu326Arg missense_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169879 p.Phe245Cys missense_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.33
PPE35 2170053 p.Thr187Ser missense_variant 0.32
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747088 p.Ala171Thr missense_variant 0.13
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087236 c.417A>C synonymous_variant 0.17
fprA 3473998 c.-9G>A upstream_gene_variant 1.0
fprA 3473998 c.-10_-9insA upstream_gene_variant 1.0
clpC1 4040605 p.Leu34Ile missense_variant 0.21
embC 4240115 p.Thr85Ala missense_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244427 p.Ser399Ala missense_variant 0.25
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407785 p.Ala140Pro missense_variant 1.0
gid 4408213 c.-11C>T upstream_gene_variant 1.0