TB-Profiler result

Run: SRR6896549
Summary

Run ID: SRR6896549

Sample name:

Date: 04-04-2023 18:09:33

Number of reads: 523682

Percentage reads mapped: 99.01

Strain: lineage4.3.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 0.99
lineage4.3.2 Euro-American (LAM) LAM3 None 0.99
lineage4.3.2.1 Euro-American (LAM) LAM3 RD761 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5520 p.Pro94Leu missense_variant 1.0
gyrA 7222 c.-80C>T upstream_gene_variant 0.94
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7757 p.Phe152Leu missense_variant 0.11
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491069 p.Leu96Arg missense_variant 0.11
mshA 576490 c.1143G>T synonymous_variant 0.12
mshA 576738 p.Val464Ala missense_variant 0.12
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303919 p.Arg330Leu missense_variant 0.11
Rv1258c 1407287 p.Met18Ile missense_variant 0.13
atpE 1461205 c.162dupC frameshift_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 1.0
rrs 1472376 n.531G>T non_coding_transcript_exon_variant 0.13
rrl 1474070 n.413A>G non_coding_transcript_exon_variant 0.15
fabG1 1673710 p.Leu91Ile missense_variant 0.17
inhA 1673898 c.-304C>T upstream_gene_variant 0.17
tlyA 1917785 c.-155C>A upstream_gene_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169273 p.Gly447Asp missense_variant 0.12
PPE35 2169636 p.Ser326Asn missense_variant 0.12
PPE35 2170085 c.528G>C synonymous_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747355 p.Val82Ile missense_variant 0.1
pepQ 2859667 p.Gln251Arg missense_variant 0.11
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087843 p.Gly342Ser missense_variant 0.11
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
ddn 3986831 c.-13T>C upstream_gene_variant 0.13
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4040605 p.Leu34Ile missense_variant 0.12
panD 4044374 c.-93G>C upstream_gene_variant 0.1
embC 4241877 p.Val672Gly missense_variant 0.12
embC 4241965 c.2103C>A synonymous_variant 0.12
embC 4242424 p.Trp854Cys missense_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244602 p.Ala457Val missense_variant 0.12
aftB 4267585 p.Thr418Ala missense_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 0.93