TB-Profiler result

Run: SRR6982064
Summary

Run ID: SRR6982064

Sample name:

Date: 04-04-2023 18:26:11

Number of reads: 299830

Percentage reads mapped: 93.25

Strain: lineage4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777400 p.Thr361Ala missense_variant 0.22
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.15
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.19
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.18
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.16
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.17
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.19
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.19
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.18
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.17
rrs 1472669 n.824_825insTAGG non_coding_transcript_exon_variant 0.2
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.18
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.18
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.24
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.25
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.37
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.37
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.37
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.24
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.24
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.17
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.16
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.11
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.2
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.24
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.21
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.2
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.19
rrs 1473080 n.1235C>A non_coding_transcript_exon_variant 0.18
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.18
rrs 1473084 n.1239T>A non_coding_transcript_exon_variant 0.17
rrl 1474723 n.1066G>A non_coding_transcript_exon_variant 0.17
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.14
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.21
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.21
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.21
rrl 1474913 n.1256T>A non_coding_transcript_exon_variant 0.15
rrl 1474920 n.1263G>C non_coding_transcript_exon_variant 0.17
rrl 1475122 n.1465C>T non_coding_transcript_exon_variant 0.2
rrl 1475129 n.1472G>T non_coding_transcript_exon_variant 0.17
rrl 1475144 n.1487G>C non_coding_transcript_exon_variant 0.25
rrl 1475154 n.1497C>A non_coding_transcript_exon_variant 0.23
rrl 1475163 n.1506T>G non_coding_transcript_exon_variant 0.21
rrl 1475175 n.1518G>A non_coding_transcript_exon_variant 0.15
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.18
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.18
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.18
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.18
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.18
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.17
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.16
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.16
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.16
rrl 1476214 n.2557G>C non_coding_transcript_exon_variant 0.15
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.14
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.17
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.23
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.23
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.24
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.24
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.24
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.24
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.24
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.25
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.25
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.25
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.24
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.26
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.26
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.26
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.45
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.45
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.48
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.52
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.52
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.47
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.44
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.43
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.43
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.43
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.42
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.34
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.23
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.23
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.25
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.25
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.25
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.25
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.25
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.25
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.24
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.24
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.3
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.3
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 0.28
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.29
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.31
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.2
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.2
rrl 1476601 n.2944G>A non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2156489 c.-378C>A upstream_gene_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449214 c.712_714delTGG conservative_inframe_deletion 0.13
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3613311 c.-195T>C upstream_gene_variant 0.17
fbiA 3641447 p.Thr302Met missense_variant 1.0
rpoA 3877553 p.Glu319Lys missense_variant 1.0
ddn 3986986 p.Leu48Pro missense_variant 0.25
embC 4240897 c.1035C>G synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243314 p.Cys28Ser missense_variant 0.13
embA 4246198 p.Cys989Tyr missense_variant 0.12
embB 4247670 p.Ala386Glu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0