TB-Profiler result

Run: SRR7535059
Summary

Run ID: SRR7535059

Sample name:

Date: 04-04-2023 19:43:12

Number of reads: 3191985

Percentage reads mapped: 99.25

Strain: lineage4.6.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.1 Euro-American (Uganda) T2 RD724 1.0
lineage4.6.1.1 Euro-American T2-Uganda RD724 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7539 p.Thr80Ala missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 0.98
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475855 n.2198A>G non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154339 c.1773A>C synonymous_variant 1.0
PPE35 2169320 p.Leu431Phe missense_variant 0.32
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2986821 c.-18C>T upstream_gene_variant 0.99
ribD 2987307 p.Ala157Pro missense_variant 0.12
Rv2752c 3065279 p.Thr305Ala missense_variant 1.0
thyA 3073806 c.666C>G synonymous_variant 0.16
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3641955 p.Gly141Arg missense_variant 0.14
alr 3840262 p.His387Tyr missense_variant 1.0
clpC1 4038857 c.1848C>A synonymous_variant 0.29
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245092 c.1860C>T synonymous_variant 0.97
ethA 4328329 c.-856C>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0