TB-Profiler result

Run: SRR9224952
Summary

Run ID: SRR9224952

Sample name:

Date: 04-04-2023 22:08:06

Number of reads: 898820

Percentage reads mapped: 95.41

Strain: lineage4.3.3;lineage4.3.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.2 Euro-American (LAM) LAM3 None 0.26
lineage4.3.3 Euro-American (LAM) LAM;T RD115 0.71
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8040 p.Gly247Ser missense_variant 0.76
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 763135 p.Gly1110Val missense_variant 0.84
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpS5 779675 c.-770G>A upstream_gene_variant 0.85
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1417060 c.288A>G synonymous_variant 0.62
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 0.12
fabG1 1673277 c.-163_-162insT upstream_gene_variant 0.74
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102102 p.Tyr314Cys missense_variant 0.55
PPE35 2168355 p.Pro753Gln missense_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518919 p.Gly269Ser missense_variant 0.75
eis 2715432 c.-100C>T upstream_gene_variant 0.74
ribD 2987533 p.Gly232Ala missense_variant 0.69
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449301 c.798G>A synonymous_variant 0.74
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246984 c.471C>T synonymous_variant 0.27
embB 4247209 c.696A>G synonymous_variant 0.89
embB 4247889 p.Gly459Asp missense_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0