TB-Profiler result

Run: ERR027466
Summary

Run ID: ERR027466

Sample name:

Date: 31-03-2023 08:21:46

Number of reads: 7611219

Percentage reads mapped: 99.89

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 762249 p.Leu815Val missense_variant 0.22
rpoC 762836 c.-534C>G upstream_gene_variant 0.27
atpE 1461019 c.-26C>A upstream_gene_variant 0.21
inhA 1674952 p.Pro251Ala missense_variant 0.17
PPE35 2169320 p.Leu431Phe missense_variant 0.29
PPE35 2169866 c.747G>C synonymous_variant 0.3
pepQ 2859381 c.1038C>G synonymous_variant 0.28
fbiB 3641955 p.Gly141Arg missense_variant 0.27
clpC1 4038857 c.1848C>A synonymous_variant 0.14
clpC1 4039932 p.Gly258Val missense_variant 0.32
embC 4239842 c.-21C>A upstream_gene_variant 0.22
embC 4242425 p.Arg855Gly missense_variant 0.25
embC 4242476 p.Pro872Ala missense_variant 0.26
embC 4242822 p.Val987Gly missense_variant 0.28
ubiA 4269529 p.Ala102Gly missense_variant 0.2