TB-Profiler result

Run: ERR11049048
Summary

Run ID: ERR11049048

Sample name:

Date: 31-03-2023 07:44:15

Number of reads: 1597538

Percentage reads mapped: 99.6

Strain: lineage4.6.5

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.5 Euro-American T;LAM None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
tlyA 1918647 p.Asn236Lys missense_variant 1.0 capreomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5489 p.Ile84Val missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7756 p.Phe152Ser missense_variant 0.11
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490756 c.-27T>G upstream_gene_variant 1.0
fgd1 491315 p.Gly178Ala missense_variant 0.22
mshA 576606 p.Ala420Gly missense_variant 0.17
rpoC 764534 p.Arg389Gly missense_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777298 p.Val395Ile missense_variant 0.11
mmpL5 777974 c.507C>T synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.25
inhA 1673571 c.-631C>G upstream_gene_variant 0.12
inhA 1674678 c.477C>T synonymous_variant 1.0
rpsA 1834094 c.553C>T synonymous_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918066 p.Ala43Pro missense_variant 0.25
tlyA 1918410 p.Phe157Leu missense_variant 0.23
ndh 2102817 p.Leu76Val missense_variant 0.2
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519081 p.Ala323Thr missense_variant 0.15
folC 2746995 p.Val202Ile missense_variant 1.0
Rv2752c 3064825 p.Asp456Ala missense_variant 0.13
thyX 3067335 p.Ala204Asp missense_variant 0.13
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3613094 p.Leu8* stop_gained 0.12
fbiA 3640346 c.-196delA upstream_gene_variant 1.0
clpC1 4038332 c.2373C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243585 p.Phe118Ser missense_variant 0.25
whiB6 4338200 p.Asp108His missense_variant 0.23
whiB6 4338595 c.-75delG upstream_gene_variant 1.0