TB-Profiler result

Run: ERR11068389
Summary

Run ID: ERR11068389

Sample name:

Date: 06-04-2023 10:51:13

Number of reads: 4268727

Percentage reads mapped: 99.62

Strain: lineage4.6

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5431 c.192A>C synonymous_variant 1.0
gyrB 7200 p.Glu654Ala missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8266 p.Ala322Glu missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491349 c.567T>C synonymous_variant 1.0
mshA 576119 p.Ala258Pro missense_variant 0.27
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 0.99
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101697 p.Ala449Val missense_variant 0.15
Rv1979c 2222525 p.Gly214Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519038 c.924C>A synonymous_variant 0.29
folC 2747775 c.-177C>T upstream_gene_variant 0.25
thyX 3067336 p.Ala204Thr missense_variant 0.14
fbiD 3339339 c.222G>A synonymous_variant 0.11
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3475296 p.Glu430Asp missense_variant 0.11
whiB7 3568427 p.Arg85Gly missense_variant 0.29
whiB7 3568431 c.249C>G synonymous_variant 0.27
rpoA 3878569 c.-62C>G upstream_gene_variant 0.14
rpoA 3878641 c.-134C>G upstream_gene_variant 0.29
embC 4242582 p.Ala907Val missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247889 p.Gly459Asp missense_variant 0.33
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407554 p.Arg217Trp missense_variant 1.0