TB-Profiler result

Run: ERR11081471
Summary

Run ID: ERR11081471

Sample name:

Date: 08-04-2023 23:03:15

Number of reads: 4090758

Percentage reads mapped: 99.57

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5103 c.-137C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.18
mshA 576113 p.Arg256Gly missense_variant 0.36
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154915 c.1197A>G synonymous_variant 1.0
PPE35 2168875 p.Asn580Asp missense_variant 1.0
PPE35 2169031 p.Asp528Asn missense_variant 0.17
PPE35 2169041 c.1572G>A synonymous_variant 0.35
PPE35 2169044 c.1569G>C synonymous_variant 0.39
PPE35 2169047 p.Ile522Val missense_variant 0.39
PPE35 2169053 c.1560T>C synonymous_variant 1.0
PPE35 2169056 c.1557A>G synonymous_variant 0.39
PPE35 2169059 c.1554G>A synonymous_variant 0.61
PPE35 2169063 p.Met517Thr missense_variant 1.0
PPE35 2169065 p.Ala516Ile missense_variant 0.61
PPE35 2169068 c.1545G>T synonymous_variant 0.61
PPE35 2169071 c.1542A>G synonymous_variant 0.36
PPE35 2170065 p.Ala183Gly missense_variant 0.24
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2715205 c.127delG frameshift_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.24
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087455 c.636C>T synonymous_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.71
fbiD 3339746 p.Ala210Gly missense_variant 0.5
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.99
rpoA 3878608 c.-101C>G upstream_gene_variant 0.29
rpoA 3878641 c.-134C>G upstream_gene_variant 0.42
clpC1 4039140 p.Glu522Gly missense_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.17
embB 4246584 p.Arg24Pro missense_variant 0.17
embB 4248324 p.Ala604Gly missense_variant 0.2
embB 4248328 c.1815G>C synonymous_variant 0.16
aftB 4267226 c.1611G>A synonymous_variant 1.0
whiB6 4338208 p.Pro105Gln missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0