TB-Profiler result

Run: ERR1633945
Summary

Run ID: ERR1633945

Sample name:

Date: 18-08-2022 14:48:06

Number of reads: 891443

Percentage reads mapped: 98.83

Strain: lineage2.2.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.99
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 1.0
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 1.0
lineage2.2.1.1 East-Asian (Beijing) Beijing-RD150 RD105;RD207;RD181;RD150 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490990 c.208C>T synonymous_variant 0.13
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
rpoB 760478 c.672C>A synonymous_variant 0.14
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 767079 p.Ala1237Val missense_variant 0.13
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303882 p.Val318Ile missense_variant 0.15
fbiC 1305024 c.2094C>T synonymous_variant 0.12
fabG1 1673657 p.Thr73Met missense_variant 0.14
rpsA 1833702 p.Asp54Gly missense_variant 0.12
rpsA 1834177 c.636A>C synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155011 c.1101G>C synonymous_variant 0.14
katG 2155139 p.Pro325Thr missense_variant 0.12
katG 2156114 c.-3G>A upstream_gene_variant 0.15
kasA 2518873 p.His253Gln missense_variant 0.14
eis 2714846 p.Val163Ile missense_variant 1.0
eis 2715246 c.87C>T synonymous_variant 0.12
ribD 2987515 p.Arg226His missense_variant 0.14
thyA 3073806 c.666C>G synonymous_variant 0.27
fbiB 3642772 p.Asp413Ala missense_variant 0.29
alr 3840446 c.975G>T synonymous_variant 0.14
alr 3840516 p.Pro302Gln missense_variant 0.14
alr 3841413 p.Arg3Gln missense_variant 0.12
panD 4044360 c.-79C>T upstream_gene_variant 0.13
embC 4239803 c.-60C>G upstream_gene_variant 0.13
embC 4239842 c.-21C>A upstream_gene_variant 0.18
embC 4242133 c.2271G>A synonymous_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embB 4248115 c.1602C>T synonymous_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0