TB-Profiler result

Run: ERR2229111
Summary

Run ID: ERR2229111

Sample name:

Date: 18-08-2022 11:16:20

Number of reads: 634371

Percentage reads mapped: 99.44

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6959 p.Gln574* stop_gained 0.14
rpoB 760139 c.333A>G synonymous_variant 0.13
rpoC 764435 p.Arg356Gly missense_variant 0.13
rpoC 767115 p.Lys1249Met missense_variant 0.15
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.18
fabG1 1673346 c.-94C>G upstream_gene_variant 0.16
fabG1 1673349 c.-91G>C upstream_gene_variant 0.2
fabG1 1673380 c.-60C>G upstream_gene_variant 0.44
fabG1 1673783 p.Gly115Glu missense_variant 0.2
inhA 1673865 c.-337C>T upstream_gene_variant 0.15
rpsA 1833441 c.-101C>A upstream_gene_variant 0.15
thyA 3074091 c.381C>A synonymous_variant 0.12
alr 3840972 p.Arg150Pro missense_variant 0.17
alr 3841162 p.Ala87Pro missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ubiA 4269838 c.-5C>G upstream_gene_variant 0.15
ethR 4328031 c.484_485insTG frameshift_variant 0.18