TB-Profiler result

Run: ERR4024524
Summary

Run ID: ERR4024524

Sample name:

Date: 01-04-2023 04:00:46

Number of reads: 2136254

Percentage reads mapped: 99.62

Strain: lineage4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 0.42
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 0.42
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6052 p.Ile271Met missense_variant 0.38
gyrB 7221 p.Ser661Thr missense_variant 0.38
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 761889 p.Val695Leu missense_variant 0.6
rpoC 765150 p.Gly594Glu missense_variant 0.46
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801009 c.201A>G synonymous_variant 0.51
embR 1416699 p.Leu217Val missense_variant 0.47
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1673865 c.-337C>T upstream_gene_variant 0.3
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223214 c.-50A>C upstream_gene_variant 0.63
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3065517 c.675C>T synonymous_variant 0.63
ald 3086788 c.-32T>C upstream_gene_variant 0.36
Rv3083 3448439 c.-64delA upstream_gene_variant 0.62
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.48
fprA 3474299 p.Asp98Gly missense_variant 0.57
rpoA 3878595 c.-88C>T upstream_gene_variant 0.18
rpoA 3878635 c.-128C>T upstream_gene_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 0.45
embB 4249408 c.2895G>A synonymous_variant 0.4
ethA 4328317 c.-844C>T upstream_gene_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0