TB-Profiler result

Run: ERR4815071

Summary

Run ID: ERR4815071

Sample name:

Date: 01-04-2023 13:39:09

Number of reads: 592398

Percentage reads mapped: 99.21

Strain: lineage3

Drug-resistance: Sensitive


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759620 c.-187A>C upstream_gene_variant 0.33
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 760547 c.741G>A synonymous_variant 0.17
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777119 p.His454Gln missense_variant 0.12
mmpL5 777122 c.1359C>T synonymous_variant 0.13
mmpL5 777128 c.1353A>G synonymous_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.23
embR 1416316 c.1032C>G synonymous_variant 0.2
embR 1416323 p.Asn342Thr missense_variant 0.2
atpE 1460912 c.-132delG upstream_gene_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167865 c.2748G>C synonymous_variant 0.2
PPE35 2167868 c.2745A>C synonymous_variant 0.2
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169308 c.1305C>T synonymous_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
pncA 2289794 c.-553A>C upstream_gene_variant 0.2
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
pepQ 2860275 p.Asp48Glu missense_variant 0.15
ribD 2987465 c.627C>T synonymous_variant 0.12
Rv2752c 3064951 p.Gly414Asp missense_variant 0.11
Rv2752c 3065163 c.1029C>T synonymous_variant 0.14
thyA 3074645 c.-174T>G upstream_gene_variant 0.22
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086960 c.141C>T synonymous_variant 1.0
Rv3083 3448396 c.-108T>G upstream_gene_variant 0.18
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474143 p.Trp46Tyr missense_variant 0.12
whiB7 3568515 c.165G>A synonymous_variant 0.12
clpC1 4039188 c.1516dupC frameshift_variant 0.13
embC 4240073 p.Glu71Lys missense_variant 1.0
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267810 c.1027C>T synonymous_variant 0.12
ethA 4326985 p.His163Gln missense_variant 0.12
ethA 4327504 c.-31G>A upstream_gene_variant 0.15
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0