TB-Profiler result

Run: ERR4816650
Summary

Run ID: ERR4816650

Sample name:

Date: 01-04-2023 14:32:53

Number of reads: 2041350

Percentage reads mapped: 98.78

Strain: lineage4.1.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 763501 c.132C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.36
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.36
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.36
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.36
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.5
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.55
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.5
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.71
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.38
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.29
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.33
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.2
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.25
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.25
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.25
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.25
rrs 1473291 n.1446G>C non_coding_transcript_exon_variant 0.15
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 0.21
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.21
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.21
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.21
rrl 1473626 n.-32C>T upstream_gene_variant 0.15
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 1.0
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 1.0
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 1.0
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 1.0
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 1.0
rrl 1476295 n.2638C>A non_coding_transcript_exon_variant 1.0
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 1.0
rrl 1476306 n.2649A>G non_coding_transcript_exon_variant 1.0
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 1.0
rrl 1476311 n.2654G>T non_coding_transcript_exon_variant 1.0
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.4
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.33
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.29
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.29
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.33
tlyA 1917795 c.-145G>C upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087494 c.675C>T synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0