TB-Profiler result

Run: ERR4818269
Summary

Run ID: ERR4818269

Sample name:

Date: 01-04-2023 15:27:53

Number of reads: 164050

Percentage reads mapped: 98.64

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6170 p.His311Asn missense_variant 0.25
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 760099 p.Ser98* stop_gained 1.0
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoB 762834 p.Gly1010Cys missense_variant 0.67
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800805 c.-4A>G upstream_gene_variant 0.5
embR 1416433 c.915C>T synonymous_variant 0.29
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673548 p.Ala37Thr missense_variant 0.4
inhA 1673616 c.-586A>G upstream_gene_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
Rv2752c 3064864 p.Pro443Leu missense_variant 0.25
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3474339 p.Met111Ile missense_variant 0.29
fbiB 3641772 p.Asp80Tyr missense_variant 0.18
fbiB 3642877 p.Lys448Arg missense_variant 1.0
alr 3840287 c.1134C>T synonymous_variant 0.4
rpoA 3878077 p.Arg144Leu missense_variant 0.33
embC 4242075 p.Arg738Gln missense_variant 1.0
embC 4242173 p.Ala771Thr missense_variant 0.33
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247579 c.1068dupC frameshift_variant 0.5
gid 4407588 c.615A>G synonymous_variant 1.0