TB-Profiler result

Run: ERR4819050
Summary

Run ID: ERR4819050

Sample name:

Date: 01-04-2023 15:53:49

Number of reads: 480654

Percentage reads mapped: 99.04

Strain: lineage3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6304 c.-998C>A upstream_gene_variant 0.29
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7926 p.Asp209Asn missense_variant 0.29
gyrA 8398 p.Val366Gly missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575570 p.Ser75Gly missense_variant 0.13
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoB 762637 p.Lys944Arg missense_variant 0.13
rpoB 762734 p.Glu976Asp missense_variant 0.12
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 778092 c.388delT frameshift_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801150 c.342G>T synonymous_variant 0.18
rplC 801392 p.Lys195Arg missense_variant 0.17
fbiC 1304510 p.Ala527Val missense_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673405 c.-35T>C upstream_gene_variant 0.17
fabG1 1673947 p.Glu170Lys missense_variant 1.0
inhA 1674233 p.Leu11Gln missense_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154077 p.Gln679Lys missense_variant 0.17
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169031 p.Asp528Asn missense_variant 0.12
Rv1979c 2222348 p.Val273Leu missense_variant 0.33
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288756 c.486T>C synonymous_variant 0.33
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
pncA 2289784 c.-543C>A upstream_gene_variant 0.2
kasA 2518340 p.Asp76Tyr missense_variant 0.29
eis 2715303 p.Glu10Asp missense_variant 0.15
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
Rv2752c 3064846 p.Val449Ala missense_variant 0.22
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3338986 c.-132G>C upstream_gene_variant 0.12
fbiD 3339076 c.-42G>A upstream_gene_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612359 p.Gly253Glu missense_variant 0.17
fbiB 3641608 p.Pro25His missense_variant 0.11
fbiB 3642122 p.Asp196Glu missense_variant 0.14
clpC1 4038706 p.Asn667Asp missense_variant 0.14
clpC1 4039108 c.1597C>A synonymous_variant 0.33
panD 4044198 c.84C>T synonymous_variant 0.33
embC 4240718 p.Phe286Leu missense_variant 0.5
embC 4240769 p.Val303Met missense_variant 0.17
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244659 p.Leu476Arg missense_variant 0.12
embB 4247971 c.1458C>T synonymous_variant 0.17
embB 4249192 c.2679C>T synonymous_variant 0.22
aftB 4268521 p.Tyr106His missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0