TB-Profiler result

Run: ERR4829264
Summary

Run ID: ERR4829264

Sample name:

Date: 01-04-2023 19:22:58

Number of reads: 5909082

Percentage reads mapped: 91.45

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.12
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.18
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.13
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.17
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.12
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.13
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.39
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.45
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.5
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.44
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.29
rrs 1472827 n.982G>C non_coding_transcript_exon_variant 0.15
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.15
rrs 1472887 n.1042G>C non_coding_transcript_exon_variant 0.2
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.2
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.12
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.11
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.12
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.12
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.33
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.3
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.31
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.33
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.3
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.27
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474218 n.561T>C non_coding_transcript_exon_variant 0.17
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 1.0
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.17
rrl 1474476 n.819C>G non_coding_transcript_exon_variant 0.12
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.14
fabG1 1673162 c.-278T>C upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155595 c.517C>T synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
Rv3236c 3612047 p.Ala357Val missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246820 p.Pro103Thr missense_variant 1.0
embB 4248094 c.1581C>T synonymous_variant 1.0
ethA 4326505 c.969C>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0