TB-Profiler result

Run: ERR551491
Summary

Run ID: ERR551491

Sample name:

Date: 15-08-2022 10:48:27

Number of reads: 776743

Percentage reads mapped: 99.62

Strain: lineage4.1.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9695 c.2396delA frameshift_variant 0.11
fgd1 491488 p.Asp236Asn missense_variant 0.12
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoB 761327 c.1521A>G synonymous_variant 0.12
rpoC 764267 p.Ala300Ser missense_variant 0.1
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775925 c.2555delT frameshift_variant 0.13
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1461193 p.Phe50Ser missense_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473443 n.-215T>C upstream_gene_variant 0.1
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.2
inhA 1673619 c.-583T>C upstream_gene_variant 0.1
inhA 1674205 p.Thr2Ala missense_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168087 c.2524_2525delCC frameshift_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
folC 2747010 p.Ile197Leu missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612773 p.Gly115Asp missense_variant 1.0
fbiB 3642271 p.Ala246Asp missense_variant 0.11
panD 4044118 p.Leu55Pro missense_variant 0.1
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249024 c.2511C>T synonymous_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0