TB-Profiler result

Run: ERR552038
Summary

Run ID: ERR552038

Sample name:

Date: 15-08-2022 10:46:11

Number of reads: 404323

Percentage reads mapped: 99.4

Strain:

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5671 c.432C>T synonymous_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759837 c.33_44dupTAGTCCTAGTCC disruptive_inframe_insertion 1.0
rpoB 761848 p.Cys681Tyr missense_variant 0.12
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpR5 779312 p.Ile108Thr missense_variant 0.18
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781814 c.255C>A synonymous_variant 0.18
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
fbiC 1304959 p.Arg677Cys missense_variant 0.2
fbiC 1305399 p.Glu823Asp missense_variant 1.0
embR 1416380 p.Ala323Val missense_variant 0.14
embR 1416549 p.Lys267Glu missense_variant 0.18
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473079 n.1234G>A non_coding_transcript_exon_variant 1.0
rpsA 1834289 c.749delA frameshift_variant 0.14
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156056 p.Gly19Val missense_variant 1.0
PPE35 2168984 c.1626_1628dupAAC disruptive_inframe_insertion 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2518328 p.Met72Val missense_variant 1.0
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
fprA 3474123 c.117G>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
whiB7 3568592 p.Ala30Ser missense_variant 0.18
ddn 3987111 p.Leu90Val missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4246864 c.351C>T synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
aftB 4268552 p.Met95Ile missense_variant 0.14
whiB6 4338595 c.-75delG upstream_gene_variant 1.0