TB-Profiler result

Run: ERR6866049
Summary

Run ID: ERR6866049

Sample name:

Date: 02-04-2023 03:13:48

Number of reads: 1069172

Percentage reads mapped: 54.84

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6346 c.-956C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302954 c.24G>A synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472912 n.1067C>T non_coding_transcript_exon_variant 0.56
rrs 1472917 n.1072G>A non_coding_transcript_exon_variant 0.56
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.42
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.42
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.42
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.42
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.5
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.4
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 0.4
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.36
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.36
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.36
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.36
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.3
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.3
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.33
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.33
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.33
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.25
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.42
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.5
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.5
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.47
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.47
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.5
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.5
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.47
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.47
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.47
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.47
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.47
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.57
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.57
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.54
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.54
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.54
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.58
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.58
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.62
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.43
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154678 c.1434G>C synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726409 p.Asp73His missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
embB 4249678 c.3165C>A synonymous_variant 1.0