TB-Profiler result

Run: SRR10808501
Summary

Run ID: SRR10808501

Sample name:

Date: 02-04-2023 18:56:34

Number of reads: 868969

Percentage reads mapped: 99.74

Strain: lineage2.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.1 East-Asian (non-Beijing) None None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7795 p.Val165Ala missense_variant 0.13
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.4
rpoC 763031 c.-339T>C upstream_gene_variant 0.96
rpoC 765121 c.1752G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304443 p.Ala505Thr missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476012 n.2355T>C non_coding_transcript_exon_variant 0.1
fabG1 1673346 c.-94C>G upstream_gene_variant 0.12
fabG1 1673349 c.-91G>C upstream_gene_variant 0.12
fabG1 1673380 c.-60C>G upstream_gene_variant 0.11
rpsA 1834177 c.636A>C synonymous_variant 0.96
rpsA 1834588 c.1047C>T synonymous_variant 1.0
rpsA 1834914 p.Lys458Arg missense_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102835 p.Pro70Ser missense_variant 0.14
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155506 c.606C>A synonymous_variant 1.0
katG 2156335 c.-224C>T upstream_gene_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.5
PPE35 2170053 p.Thr187Ser missense_variant 0.54
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747463 p.Ser46Cys missense_variant 0.11
thyX 3067340 c.606G>A synonymous_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4040841 c.-138delG upstream_gene_variant 1.0
embC 4241063 p.Ile401Phe missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4245716 c.-798G>A upstream_gene_variant 0.17
embB 4246088 c.-426A>G upstream_gene_variant 1.0
embB 4246544 p.Thr11Pro missense_variant 0.27
embB 4246548 p.Pro12Gln missense_variant 0.3
embB 4246555 c.42G>C synonymous_variant 0.43
embB 4246556 p.Ala15Pro missense_variant 0.43
embB 4246563 p.Leu17Trp missense_variant 0.33
embB 4246567 c.54G>T synonymous_variant 0.29
aftB 4267647 p.Asp397Gly missense_variant 1.0
aftB 4269471 c.-635C>G upstream_gene_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0