Run ID: SRR12142410
Sample name:
Date: 03-04-2023 06:27:31
Number of reads: 9004119
Percentage reads mapped: 99.26
Strain: lineage4.4.2
Drug-resistance: MDR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.4 | Euro-American | S;T | None | 0.99 |
lineage4.4.2 | Euro-American | T1;T2 | None | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761155 | p.Ser450Leu | missense_variant | 1.0 | rifampicin |
katG | 2155168 | p.Ser315Thr | missense_variant | 1.0 | isoniazid |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
mshA | 575906 | p.Ala187Thr | missense_variant | 0.99 |
rpoC | 765680 | p.Asn771Asp | missense_variant | 1.0 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.15 |
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.15 |
rrs | 1472958 | n.1113A>T | non_coding_transcript_exon_variant | 0.15 |
rrs | 1472959 | n.1114T>A | non_coding_transcript_exon_variant | 0.15 |
rrs | 1472982 | n.1137G>A | non_coding_transcript_exon_variant | 0.15 |
rrs | 1472987 | n.1142G>T | non_coding_transcript_exon_variant | 0.15 |
rrs | 1472989 | n.1144G>A | non_coding_transcript_exon_variant | 0.15 |
rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.15 |
rrs | 1472996 | n.1151T>C | non_coding_transcript_exon_variant | 0.16 |
rrs | 1473002 | n.1157G>T | non_coding_transcript_exon_variant | 0.15 |
rrs | 1473004 | n.1159T>A | non_coding_transcript_exon_variant | 0.15 |
rrs | 1473008 | n.1163C>A | non_coding_transcript_exon_variant | 0.15 |
rrs | 1473009 | n.1164T>C | non_coding_transcript_exon_variant | 0.16 |
rrs | 1473044 | n.1199C>G | non_coding_transcript_exon_variant | 0.13 |
rrs | 1473051 | n.1206T>C | non_coding_transcript_exon_variant | 0.1 |
rrs | 1473053 | n.1208T>G | non_coding_transcript_exon_variant | 0.1 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
Rv1979c | 2223230 | c.-66C>T | upstream_gene_variant | 0.88 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
Rv2752c | 3066099 | p.Met31Ile | missense_variant | 1.0 |
Rv2752c | 3067109 | c.-918T>A | upstream_gene_variant | 1.0 |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 |
Rv3083 | 3448727 | p.Leu75Arg | missense_variant | 0.99 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
rpoA | 3877952 | p.Arg186Cys | missense_variant | 0.94 |
clpC1 | 4039058 | p.Phe549Leu | missense_variant | 0.99 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 0.99 |
embA | 4243991 | c.759T>G | synonymous_variant | 0.99 |
embB | 4246508 | c.-6G>A | upstream_gene_variant | 0.99 |
aftB | 4268928 | c.-92C>T | upstream_gene_variant | 1.0 |
aftB | 4269375 | c.-539G>A | upstream_gene_variant | 0.99 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
gid | 4407656 | p.Ala183Pro | missense_variant | 0.99 |