TB-Profiler result

Run: SRR12634543
Summary

Run ID: SRR12634543

Sample name:

Date: 03-04-2023 06:53:09

Number of reads: 1967294

Percentage reads mapped: 63.46

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.11
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.12
rrs 1472153 n.308G>A non_coding_transcript_exon_variant 0.13
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.14
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.16
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.15
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.14
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.16
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.12
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.19
rrs 1472553 n.708C>T non_coding_transcript_exon_variant 0.22
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.25
rrs 1472572 n.727T>C non_coding_transcript_exon_variant 0.22
rrs 1472574 n.729T>C non_coding_transcript_exon_variant 0.21
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 0.21
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 0.22
rrs 1472583 n.738T>A non_coding_transcript_exon_variant 0.22
rrs 1472584 n.739A>G non_coding_transcript_exon_variant 0.22
rrs 1472594 n.749G>C non_coding_transcript_exon_variant 0.27
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.29
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.32
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.24
rrs 1472658 n.813G>T non_coding_transcript_exon_variant 0.2
rrs 1472659 n.814G>C non_coding_transcript_exon_variant 0.19
rrs 1472660 n.815T>G non_coding_transcript_exon_variant 0.19
rrs 1472664 n.819A>T non_coding_transcript_exon_variant 0.17
rrs 1472666 n.821_822insAGGT non_coding_transcript_exon_variant 0.18
rrs 1472686 n.842_844delATC non_coding_transcript_exon_variant 0.18
rrs 1472707 n.862A>G non_coding_transcript_exon_variant 0.18
rrs 1472714 n.869A>C non_coding_transcript_exon_variant 0.19
rrs 1472715 n.870C>G non_coding_transcript_exon_variant 0.19
rrs 1472716 n.871C>A non_coding_transcript_exon_variant 0.19
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.27
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.26
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.27
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.2
rrs 1472912 n.1067C>T non_coding_transcript_exon_variant 0.13
rrs 1472917 n.1072G>A non_coding_transcript_exon_variant 0.15
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.13
rrs 1473206 n.1361G>A non_coding_transcript_exon_variant 0.13
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475791 n.2134A>G non_coding_transcript_exon_variant 0.11
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.12
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.11
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.22
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.27
rrl 1475874 n.2217C>T non_coding_transcript_exon_variant 0.14
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.4
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.46
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.45
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.46
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.49
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.49
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.5
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.48
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.48
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.47
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.47
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.47
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.42
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.43
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.4
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.41
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.41
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.41
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.41
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.41
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.16
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103202 c.-160C>A upstream_gene_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4247395 c.882C>T synonymous_variant 1.0
whiB6 4338290 c.231delA frameshift_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0