TB-Profiler result

Run: SRR13837920

Summary

Run ID: SRR13837920

Sample name:

Date: 03-04-2023 09:22:04

Number of reads: 1488050

Percentage reads mapped: 97.24

Strain: lineage4.9

Drug-resistance: Other


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
embB 4247448 p.His312Arg missense_variant 0.15 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5417 p.Gly60Ser missense_variant 1.0
gyrB 6381 p.Lys381Arg missense_variant 1.0
fgd1 491364 c.582T>C synonymous_variant 1.0
fgd1 491557 p.Lys259* stop_gained 0.98
rpoB 760985 c.1179G>C synonymous_variant 0.11
rpoC 763034 c.-336C>G upstream_gene_variant 0.12
rpoC 763040 c.-330C>G upstream_gene_variant 0.12
rpoC 763076 c.-294C>G upstream_gene_variant 0.12
Rv1258c 1406579 c.762C>T synonymous_variant 1.0
rrl 1473445 n.-213G>T upstream_gene_variant 1.0
rrl 1475387 n.1730C>T non_coding_transcript_exon_variant 0.98
fabG1 1673735 p.Arg99Leu missense_variant 1.0
inhA 1674246 c.45C>T synonymous_variant 1.0
inhA 1674937 c.736C>T synonymous_variant 0.98
rpsA 1833345 c.-196delC upstream_gene_variant 1.0
PPE35 2170775 c.-163T>A upstream_gene_variant 1.0
pncA 2289663 c.-422A>G upstream_gene_variant 1.0
pncA 2290143 c.-903_-902insG upstream_gene_variant 1.0
eis 2714984 p.Ala117Thr missense_variant 1.0
ahpC 2726534 c.342C>T synonymous_variant 1.0
thyA 3074240 p.Thr78Ser missense_variant 1.0
ald 3086806 c.-14_-13insA upstream_gene_variant 1.0
Rv3083 3448862 p.Gly120Ala missense_variant 1.0
fprA 3473896 c.-110delA upstream_gene_variant 1.0
alr 3840667 p.Arg252Gly missense_variant 1.0
rpoA 3878142 c.366C>G synonymous_variant 1.0
clpC1 4040117 p.Glu196Asp missense_variant 0.96
embA 4242988 c.-245A>G upstream_gene_variant 1.0
embB 4247437 c.924A>G synonymous_variant 0.16
embB 4247440 c.927C>G synonymous_variant 0.16
embB 4247464 c.951C>G synonymous_variant 0.14
embB 4247470 c.957T>C synonymous_variant 0.13
ubiA 4269624 p.Tyr70* stop_gained 1.0
ethR 4328039 p.Arg164Pro missense_variant 1.0
whiB6 4338235 p.Arg96Leu missense_variant 1.0