TB-Profiler result

Run: SRR13861441
Summary

Run ID: SRR13861441

Sample name:

Date: 03-04-2023 09:31:59

Number of reads: 1450805

Percentage reads mapped: 24.2

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6561 p.Lys441Arg missense_variant 1.0
gyrA 7705 p.Thr135Ser missense_variant 1.0
gyrA 8409 p.Leu370Ile missense_variant 1.0
ccsA 620157 c.267G>T synonymous_variant 1.0
rplC 801215 c.408delC frameshift_variant 1.0
fbiC 1304409 c.1479C>G synonymous_variant 1.0
fbiC 1304501 p.Ala524Gly missense_variant 1.0
rrs 1472791 n.946G>C non_coding_transcript_exon_variant 1.0
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.19
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.18
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.18
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.18
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.18
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.18
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.19
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.19
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.19
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.19
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.19
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.2
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.18
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.18
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.19
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.17
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.18
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.12
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.12
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.55
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.59
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.59
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.59
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.59
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.61
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.62
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.62
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.61
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.61
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.64
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.63
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.63
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.62
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.63
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.64
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.62
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.62
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.59
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.59
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.19
PPE35 2168564 c.2049T>A synonymous_variant 1.0
kasA 2519179 c.1065G>C synonymous_variant 1.0
folC 2746546 p.Asp351Glu missense_variant 1.0
thyX 3068038 c.-93C>A upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
Rv3236c 3612721 c.396G>T synonymous_variant 1.0
fbiA 3641221 p.Pro227Ala missense_variant 1.0
clpC1 4039647 p.Glu353Ala missense_variant 1.0
embC 4240006 c.144A>C synonymous_variant 1.0
embA 4244074 p.Ala281Val missense_variant 1.0
embA 4245739 p.Arg836His missense_variant 1.0
ethA 4326731 p.Ala248Gly missense_variant 1.0
ethR 4327623 c.75_76insC frameshift_variant 1.0
gid 4408334 c.-132G>T upstream_gene_variant 1.0