TB-Profiler result

Run: SRR13861663
Summary

Run ID: SRR13861663

Sample name:

Date: 03-04-2023 09:37:29

Number of reads: 212706

Percentage reads mapped: 10.65

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6561 p.Lys441Arg missense_variant 1.0
gyrA 7084 c.-218A>G upstream_gene_variant 0.25
gyrA 7523 c.222C>G synonymous_variant 0.13
gyrA 7532 c.231T>C synonymous_variant 0.2
gyrA 7541 c.240C>G synonymous_variant 0.23
gyrA 7585 p.Ser95Thr missense_variant 0.15
gyrA 7626 c.325C>T synonymous_variant 0.15
gyrA 7670 c.369A>G synonymous_variant 0.2
gyrA 7676 c.375G>C synonymous_variant 0.27
gyrA 7683 c.382A>C synonymous_variant 0.2
gyrA 7694 c.393A>G synonymous_variant 0.25
gyrA 7697 c.396C>G synonymous_variant 0.25
gyrA 7705 p.Thr135Ser missense_variant 0.77
gyrA 7710 c.409T>C synonymous_variant 0.25
gyrA 7715 c.414G>C synonymous_variant 0.25
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.27
gyrA 7760 c.459C>T synonymous_variant 0.27
gyrA 7763 c.462T>C synonymous_variant 0.27
gyrA 7799 c.498A>G synonymous_variant 0.31
gyrA 7835 c.534A>G synonymous_variant 0.18
gyrA 7838 c.537C>G synonymous_variant 0.2
gyrA 7859 c.558A>C synonymous_variant 0.3
gyrA 7862 c.561C>G synonymous_variant 0.3
gyrA 7865 c.564T>C synonymous_variant 0.3
gyrA 7883 c.582G>C synonymous_variant 0.3
gyrA 7884 p.Arg195Gly missense_variant 0.3
gyrA 7892 c.591G>C synonymous_variant 0.33
gyrA 7898 p.Asp199Glu missense_variant 0.33
gyrA 7919 p.Glu206Asp missense_variant 0.38
gyrA 7923 p.His208Tyr missense_variant 0.33
gyrA 7928 p.Asp209Glu missense_variant 0.33
gyrA 7942 p.Glu214Ala missense_variant 0.5
gyrA 7955 c.654G>C synonymous_variant 0.29
gyrA 7958 c.657C>G synonymous_variant 0.29
gyrA 7963 p.Gly221Glu missense_variant 0.33
gyrA 7970 c.669T>G synonymous_variant 0.33
gyrA 7976 c.675C>A synonymous_variant 0.33
gyrA 7979 c.678G>C synonymous_variant 0.33
gyrA 7992 p.Ala231Ser missense_variant 0.33
gyrA 7997 c.696A>C synonymous_variant 0.33
gyrA 8391 p.Tyr364His missense_variant 0.19
gyrA 8399 c.1098T>C synonymous_variant 0.14
gyrA 8409 p.Leu370Ile missense_variant 0.85
gyrA 8420 c.1119T>C synonymous_variant 0.17
gyrA 8423 c.1122G>C synonymous_variant 0.17
gyrA 8442 c.1141C>T synonymous_variant 0.15
gyrA 8453 c.1152A>C synonymous_variant 0.15
gyrA 8462 c.1161A>G synonymous_variant 0.17
gyrA 8471 c.1170T>C synonymous_variant 0.23
gyrA 8480 c.1179C>T synonymous_variant 0.25
gyrA 8486 c.1185T>C synonymous_variant 0.25
gyrA 8489 c.1188A>G synonymous_variant 0.25
gyrA 8498 c.1197C>T synonymous_variant 0.27
gyrA 8504 c.1203G>C synonymous_variant 0.3
gyrA 8516 c.1215T>C synonymous_variant 0.33
gyrA 8519 c.1218A>C synonymous_variant 0.25
fgd1 491145 c.363C>G synonymous_variant 0.33
fgd1 491166 c.384G>C synonymous_variant 0.33
fgd1 491212 p.Ser144Arg missense_variant 0.33
fgd1 491217 c.435T>C synonymous_variant 0.4
fgd1 491232 c.450T>C synonymous_variant 0.33
fgd1 491241 p.Asp153Glu missense_variant 0.4
fgd1 491244 c.462T>C synonymous_variant 0.4
fgd1 491259 c.477T>C synonymous_variant 0.4
fgd1 491286 c.504G>C synonymous_variant 0.67
fgd1 491292 c.510G>C synonymous_variant 0.67
mshA 575638 c.291T>C synonymous_variant 0.33
ccsA 620157 c.267G>T synonymous_variant 1.0
ccsA 620245 c.355T>C synonymous_variant 0.29
ccsA 620249 p.Ser120Cys missense_variant 0.29
ccsA 620254 c.364_366delCTCinsTTG synonymous_variant 0.29
ccsA 620257 p.Ile123Val missense_variant 0.29
ccsA 620265 c.375C>G synonymous_variant 0.29
ccsA 620269 p.Val127Ile missense_variant 0.29
ccsA 620275 c.385C>T synonymous_variant 0.33
ccsA 620283 c.393T>C synonymous_variant 0.33
ccsA 620284 p.Ala132Pro missense_variant 0.33
ccsA 620288 p.Arg133Gln missense_variant 0.33
ccsA 620295 c.405G>C synonymous_variant 0.4
ccsA 620307 c.417C>G synonymous_variant 0.4
ccsA 620340 c.450C>G synonymous_variant 0.29
ccsA 620349 c.459A>G synonymous_variant 0.33
rpoB 761015 c.1209G>C synonymous_variant 0.17
rpoB 761021 c.1215G>C synonymous_variant 0.17
rpoB 761027 c.1221A>G synonymous_variant 0.17
rpoB 761036 c.1230G>C synonymous_variant 0.18
rpoB 761037 c.1231T>C synonymous_variant 0.18
rpoB 761051 c.1245G>T synonymous_variant 0.18
rpoB 761054 c.1248G>C synonymous_variant 0.18
rpoB 761057 c.1251G>C synonymous_variant 0.17
rpoB 761060 c.1254C>G synonymous_variant 0.17
rpoB 761063 c.1257C>G synonymous_variant 0.15
rpoB 761102 c.1296A>G synonymous_variant 0.27
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.27
rpoB 761150 c.1344A>C synonymous_variant 0.25
rpoB 761165 c.1359G>C synonymous_variant 0.29
rpoB 761168 c.1362C>G synonymous_variant 0.29
rpoB 761171 c.1365C>T synonymous_variant 0.21
rpoB 761180 c.1374A>C synonymous_variant 0.29
rpoB 761183 c.1377T>G synonymous_variant 0.21
rpoB 761189 c.1383T>G synonymous_variant 0.21
rpoB 761222 c.1416G>C synonymous_variant 0.42
rpoB 761249 c.1443A>G synonymous_variant 0.4
rpoB 761255 c.1449T>G synonymous_variant 0.33
rpoB 761261 c.1455G>T synonymous_variant 0.29
rpoB 761648 c.1842T>C synonymous_variant 0.18
rpoB 761657 c.1851C>G synonymous_variant 0.18
rpoB 761765 c.1959T>C synonymous_variant 0.25
rpoB 761772 p.His656Ala missense_variant 0.22
rpoB 761778 p.Asn658Asp missense_variant 0.22
rpoB 761791 p.Arg662His missense_variant 0.2
rpoB 761948 c.2142G>C synonymous_variant 0.33
rpoB 761954 c.2148C>G synonymous_variant 0.33
rpoB 761999 c.2193G>C synonymous_variant 0.29
rpoB 762008 c.2202C>G synonymous_variant 0.25
rpoB 762014 c.2208C>T synonymous_variant 0.25
rpoB 762017 c.2211A>G synonymous_variant 0.25
rpoB 762027 c.2221_2223delCTCinsTTG synonymous_variant 0.29
rpoB 762032 c.2226C>G synonymous_variant 0.29
rpoB 762035 c.2229G>C synonymous_variant 0.29
rpoB 762053 c.2247T>C synonymous_variant 0.29
rpoB 762218 c.2412T>G synonymous_variant 0.25
rpoB 762254 c.2448T>C synonymous_variant 0.22
rpoB 762266 c.2460T>C synonymous_variant 0.22
rpoB 762284 c.2478G>C synonymous_variant 0.18
rpoB 762293 c.2487T>C synonymous_variant 0.17
rpoB 762338 c.2532T>C synonymous_variant 0.14
rpoC 762989 c.-381G>C upstream_gene_variant 0.25
rpoC 762995 c.-375G>T upstream_gene_variant 0.25
rpoC 763546 c.177A>G synonymous_variant 0.22
rpoC 763594 c.225C>T synonymous_variant 0.29
rpoC 763633 c.264T>C synonymous_variant 0.5
rpoC 763636 c.267T>C synonymous_variant 0.5
rpoC 763642 c.273G>C synonymous_variant 0.6
rpoC 763658 c.289_291delCTTinsTTG synonymous_variant 0.6
rpoC 763675 c.306C>G synonymous_variant 0.67
rpoC 763696 c.327T>C synonymous_variant 0.5
rpoC 763702 c.333C>G synonymous_variant 0.6
rpoC 763708 c.339G>A synonymous_variant 0.6
rpoC 763709 c.340C>T synonymous_variant 0.6
rpoC 763714 c.345G>C synonymous_variant 0.6
rpoC 763717 c.348T>C synonymous_variant 0.6
rpoC 763723 c.354G>C synonymous_variant 0.6
rpoC 763732 c.363C>G synonymous_variant 0.5
rpoC 763735 c.366G>C synonymous_variant 0.4
rpoC 763744 c.375G>C synonymous_variant 0.4
rpoC 763765 c.396T>C synonymous_variant 0.4
rpoC 763768 c.399C>G synonymous_variant 0.4
rpoC 763780 c.411C>G synonymous_variant 0.4
rpoC 763801 c.432C>G synonymous_variant 0.4
rpoC 764387 c.1018T>C synonymous_variant 0.27
rpoC 764401 c.1032C>T synonymous_variant 0.31
rpoC 764404 c.1035C>T synonymous_variant 0.31
rpoC 764405 c.1036A>C synonymous_variant 0.38
rpoC 764419 c.1050C>T synonymous_variant 0.29
rpoC 764428 c.1059G>T synonymous_variant 0.29
rpoC 764434 c.1065A>G synonymous_variant 0.29
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.29
rpoC 764441 p.Ile358Leu missense_variant 0.29
rpoC 764446 c.1077T>C synonymous_variant 0.36
rpoC 764451 p.Gly361Ala missense_variant 0.29
rpoC 764455 c.1086G>T synonymous_variant 0.31
rpoC 764461 p.Glu364Asp missense_variant 0.29
rpoC 764470 c.1101C>G synonymous_variant 0.31
rpoC 764471 p.Asn368Arg missense_variant 0.29
rpoC 764479 c.1110G>A synonymous_variant 0.27
rpoC 764485 c.1116G>C synonymous_variant 0.29
rpoC 764498 p.Ser377Ala missense_variant 0.42
rpoC 764503 c.1134G>C synonymous_variant 0.38
rpoC 764509 c.1140G>C synonymous_variant 0.36
rpoC 764513 p.Phe382Leu missense_variant 0.33
rpoC 764521 c.1152T>C synonymous_variant 0.36
rpoC 764527 c.1158C>T synonymous_variant 0.23
rpoC 764536 c.1167G>C synonymous_variant 0.18
rpoC 764560 c.1191T>C synonymous_variant 0.15
rpoC 764566 c.1197C>G synonymous_variant 0.17
rpoC 764573 c.1204_1206delCTTinsTTG synonymous_variant 0.17
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.18
rpoC 764581 c.1212T>C synonymous_variant 0.25
rpoC 764626 c.1257C>T synonymous_variant 0.22
rpoC 764632 c.1263T>C synonymous_variant 0.29
rpoC 764644 c.1275G>C synonymous_variant 0.25
rpoC 764650 c.1281G>T synonymous_variant 0.25
rpoC 765658 c.2289C>T synonymous_variant 0.18
rpoC 765700 c.2331T>C synonymous_variant 0.17
rpoC 765734 c.2365T>C synonymous_variant 0.2
rpoC 765739 c.2370G>C synonymous_variant 0.19
rpoC 765751 c.2382C>G synonymous_variant 0.19
rpoC 765753 p.Asp795Ala missense_variant 0.19
rpoC 765772 c.2403C>G synonymous_variant 0.19
rpoC 765784 c.2415C>G synonymous_variant 0.18
rpoC 765796 c.2427C>T synonymous_variant 0.14
rpoC 765811 c.2442T>C synonymous_variant 0.14
rpoC 765835 c.2466C>T synonymous_variant 0.14
rpoC 766607 p.Ile1080Leu missense_variant 0.2
rpoC 766630 c.3261G>C synonymous_variant 0.18
rpoC 766651 c.3282T>C synonymous_variant 0.18
rpoC 766657 c.3288A>G synonymous_variant 0.18
rpoC 766672 c.3303T>C synonymous_variant 0.18
rpoC 766726 c.3357T>C synonymous_variant 0.18
rpoC 766738 c.3369G>T synonymous_variant 0.18
rpoC 766765 c.3396A>C synonymous_variant 0.14
rpoC 766774 c.3405T>C synonymous_variant 0.14
rpoC 766801 c.3432C>A synonymous_variant 0.17
rpoC 766804 c.3435A>G synonymous_variant 0.17
rpoC 766843 c.3474T>C synonymous_variant 0.25
rpoC 766861 c.3492G>C synonymous_variant 0.2
rpoC 766864 c.3495G>C synonymous_variant 0.22
mmpL5 775966 p.Ala839Ser missense_variant 0.4
rpsL 781832 c.273T>C synonymous_variant 0.22
rpsL 781841 c.282C>G synonymous_variant 0.22
rpsL 781859 c.300T>C synonymous_variant 0.2
rpsL 781868 c.309T>C synonymous_variant 0.2
rpsL 781871 c.312G>C synonymous_variant 0.2
rpsL 781892 c.333A>G synonymous_variant 0.29
rpsL 781898 c.339A>T synonymous_variant 0.29
rpsL 781916 c.357T>C synonymous_variant 0.33
rpsL 781929 p.Gly124Ser missense_variant 0.4
rplC 801215 c.408delC frameshift_variant 1.0
rplC 801410 p.Arg201Pro missense_variant 0.4
fbiC 1303674 c.744C>G synonymous_variant 0.33
fbiC 1303686 c.756C>G synonymous_variant 0.4
fbiC 1303695 c.765T>C synonymous_variant 0.6
fbiC 1303708 c.778T>C synonymous_variant 0.6
fbiC 1303728 c.798G>A synonymous_variant 0.4
fbiC 1303730 p.Leu267Pro missense_variant 0.4
fbiC 1303732 p.Ser268Ala missense_variant 0.4
fbiC 1303737 c.807G>A synonymous_variant 0.4
fbiC 1303746 c.816T>C synonymous_variant 0.5
fbiC 1303749 c.819G>C synonymous_variant 0.5
fbiC 1303752 c.822A>G synonymous_variant 0.5
fbiC 1303755 c.825T>C synonymous_variant 0.5
fbiC 1303785 c.855G>C synonymous_variant 0.33
fbiC 1303789 p.Ile287Val missense_variant 0.33
fbiC 1303818 c.888C>G synonymous_variant 0.29
fbiC 1303836 c.906G>C synonymous_variant 0.38
fbiC 1303845 c.915C>G synonymous_variant 0.29
fbiC 1303846 p.Phe306Val missense_variant 0.29
fbiC 1303854 c.924T>C synonymous_variant 0.43
fbiC 1303860 c.930A>C synonymous_variant 0.29
fbiC 1303881 c.951G>C synonymous_variant 0.43
fbiC 1303884 c.954T>G synonymous_variant 0.43
fbiC 1303911 c.981G>C synonymous_variant 0.38
fbiC 1303914 c.984C>G synonymous_variant 0.38
fbiC 1303920 c.990C>G synonymous_variant 0.43
fbiC 1303923 c.993C>T synonymous_variant 0.43
fbiC 1303929 c.999G>C synonymous_variant 0.38
fbiC 1303947 c.1017T>C synonymous_variant 0.29
fbiC 1303948 p.Gly340Arg missense_variant 0.29
fbiC 1303969 p.Val347Ile missense_variant 0.33
fbiC 1303973 p.Gly348Ala missense_variant 0.33
fbiC 1303995 c.1065C>T synonymous_variant 0.25
fbiC 1304001 c.1071C>G synonymous_variant 0.25
fbiC 1304008 c.1078T>C synonymous_variant 0.25
fbiC 1304034 c.1104A>G synonymous_variant 0.22
fbiC 1304040 c.1110C>G synonymous_variant 0.22
fbiC 1304046 c.1116C>G synonymous_variant 0.22
fbiC 1304049 c.1119T>G synonymous_variant 0.22
fbiC 1304058 c.1128G>A synonymous_variant 0.25
fbiC 1304059 c.1129C>T synonymous_variant 0.29
fbiC 1304064 c.1134G>C synonymous_variant 0.25
fbiC 1304067 c.1137G>C synonymous_variant 0.25
fbiC 1304073 c.1143C>T synonymous_variant 0.25
fbiC 1304080 p.Ala384Ser missense_variant 0.29
fbiC 1304091 p.Asp387Glu missense_variant 0.22
fbiC 1304092 p.Met388Leu missense_variant 0.22
fbiC 1304097 c.1167G>C synonymous_variant 0.2
fbiC 1304409 c.1479C>G synonymous_variant 1.0
fbiC 1304501 p.Ala524Gly missense_variant 1.0
rrs 1472791 n.946G>C non_coding_transcript_exon_variant 1.0
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.4
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.43
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.43
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.43
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.43
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.4
rrs 1472971 n.1126G>C non_coding_transcript_exon_variant 0.43
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.38
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.38
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.31
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.38
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.38
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.4
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.4
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.4
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.4
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 0.38
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 0.29
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 0.29
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.2
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.2
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.22
rrl 1474051 n.394T>C non_coding_transcript_exon_variant 0.25
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.17
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.17
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.2
rrl 1474104 n.447G>A non_coding_transcript_exon_variant 0.22
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.25
rrl 1474112 n.455T>A non_coding_transcript_exon_variant 0.25
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.25
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.23
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.18
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.22
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.33
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.4
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.25
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.22
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.22
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.22
rrl 1475271 n.1614A>C non_coding_transcript_exon_variant 0.22
rrl 1475273 n.1616T>A non_coding_transcript_exon_variant 0.2
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.22
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.22
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.22
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.33
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.22
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.29
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.25
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.33
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.33
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.18
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.15
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.15
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.15
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.18
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.15
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.23
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.18
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.18
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.2
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.2
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.2
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.8
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.87
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.87
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.87
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.88
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.89
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.89
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.89
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.89
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.89
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.89
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.89
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.89
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.89
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.89
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.89
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.89
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.89
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.87
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.87
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.46
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.22
inhA 1674279 c.78A>C synonymous_variant 0.18
inhA 1674280 p.Arg27Lys missense_variant 0.18
inhA 1674285 c.84A>G synonymous_variant 0.18
inhA 1674301 c.102_103delCC frameshift_variant 0.18
inhA 1674307 c.106C>T synonymous_variant 0.18
inhA 1674315 c.114C>G synonymous_variant 0.2
inhA 1674321 c.120G>C synonymous_variant 0.2
inhA 1674342 c.141T>C synonymous_variant 0.3
inhA 1674352 p.Thr51Val missense_variant 0.29
inhA 1674368 p.Ala56Glu missense_variant 0.3
inhA 1674379 c.178C>T synonymous_variant 0.38
inhA 1674382 p.Leu61Ile missense_variant 0.38
inhA 1674387 c.186A>G synonymous_variant 0.38
inhA 1674399 c.198A>G synonymous_variant 0.38
rpsA 1834177 c.636A>C synonymous_variant 0.25
rpsA 1834186 c.645C>G synonymous_variant 0.25
rpsA 1834189 c.648G>C synonymous_variant 0.25
rpsA 1834195 c.654G>C synonymous_variant 0.25
PPE35 2168564 c.2049T>A synonymous_variant 1.0
kasA 2519179 c.1065G>C synonymous_variant 1.0
folC 2746546 p.Asp351Glu missense_variant 1.0
Rv2752c 3065288 c.904T>C synonymous_variant 0.38
thyX 3068038 c.-93C>A upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
Rv3236c 3612721 c.396G>T synonymous_variant 1.0
fbiA 3641221 p.Pro227Ala missense_variant 1.0
fbiB 3642143 c.609C>T synonymous_variant 0.25
fbiB 3642144 c.610T>C synonymous_variant 0.25
fbiB 3642149 c.615C>G synonymous_variant 0.25
fbiB 3642152 c.618A>G synonymous_variant 0.25
fbiB 3642169 p.Thr212Met missense_variant 0.29
fbiB 3642188 c.654T>C synonymous_variant 0.33
fbiB 3642201 p.Ser223Thr missense_variant 0.25
fbiB 3642212 c.678C>G synonymous_variant 0.29
fbiB 3642218 c.684A>C synonymous_variant 0.29
fbiB 3642227 c.693A>G synonymous_variant 0.33
fbiB 3642228 c.694C>T synonymous_variant 0.33
fbiB 3642243 p.Ala237Thr missense_variant 0.29
fbiB 3642246 p.Asn238Glu missense_variant 0.29
rpoA 3877818 c.690A>G synonymous_variant 0.4
rpoA 3877839 c.669G>C synonymous_variant 0.29
rpoA 3877857 c.651G>A synonymous_variant 0.29
rpoA 3877866 c.642G>C synonymous_variant 0.25
rpoA 3877872 c.636C>T synonymous_variant 0.25
rpoA 3877875 c.633T>G synonymous_variant 0.25
rpoA 3877899 p.Ser203Thr missense_variant 0.25
rpoA 3877905 c.603A>G synonymous_variant 0.25
rpoA 3877908 p.Asn200Ser missense_variant 0.25
rpoA 3877953 c.555G>A synonymous_variant 0.33
rpoA 3877962 c.546G>T synonymous_variant 0.29
rpoA 3877986 c.522G>C synonymous_variant 0.33
rpoA 3877989 c.519A>G synonymous_variant 0.33
rpoA 3878001 c.507A>G synonymous_variant 0.33
rpoA 3878022 c.486T>C synonymous_variant 0.33
rpoA 3878025 c.483C>T synonymous_variant 0.33
rpoA 3878028 c.480G>C synonymous_variant 0.33
rpoA 3878031 c.477T>C synonymous_variant 0.33
rpoA 3878040 c.468T>C synonymous_variant 0.33
rpoA 3878046 c.462T>C synonymous_variant 0.33
rpoA 3878049 c.459G>C synonymous_variant 0.33
rpoA 3878055 c.453A>G synonymous_variant 0.33
rpoA 3878061 c.447G>C synonymous_variant 0.33
rpoA 3878067 c.441C>G synonymous_variant 0.25
rpoA 3878070 c.438T>C synonymous_variant 0.25
rpoA 3878082 c.426T>C synonymous_variant 0.33
rpoA 3878141 p.Met123Leu missense_variant 0.33
rpoA 3878142 p.Gly122Glu missense_variant 0.33
rpoA 3878169 c.339G>C synonymous_variant 0.4
rpoA 3878184 c.324C>T synonymous_variant 0.4
rpoA 3878187 c.321C>G synonymous_variant 0.4
rpoA 3878193 c.315T>C synonymous_variant 0.4
rpoA 3878199 c.309T>C synonymous_variant 0.4
rpoA 3878202 c.306G>C synonymous_variant 0.4
rpoA 3878217 c.291A>G synonymous_variant 0.67
rpoA 3878220 c.288C>T synonymous_variant 0.67
rpoA 3878271 c.237T>C synonymous_variant 0.33
clpC1 4039409 c.1296T>C synonymous_variant 0.15
clpC1 4039647 p.Glu353Ala missense_variant 0.86
clpC1 4040354 c.351A>G synonymous_variant 0.33
clpC1 4040363 c.342A>C synonymous_variant 0.33
clpC1 4040369 c.336C>G synonymous_variant 0.33
clpC1 4040380 c.325T>C synonymous_variant 0.33
clpC1 4040381 c.324T>C synonymous_variant 0.33
clpC1 4040387 c.318A>G synonymous_variant 0.33
clpC1 4040393 c.312G>C synonymous_variant 0.4
clpC1 4040411 c.294T>C synonymous_variant 0.6
clpC1 4040423 c.282A>G synonymous_variant 0.75
clpC1 4040426 c.279T>C synonymous_variant 0.75
clpC1 4040431 c.274T>C synonymous_variant 0.67
clpC1 4040441 c.264C>G synonymous_variant 0.5
clpC1 4040444 c.261C>G synonymous_variant 0.5
clpC1 4040450 c.255A>G synonymous_variant 0.4
clpC1 4040459 c.246C>G synonymous_variant 0.4
clpC1 4040465 c.240T>C synonymous_variant 0.4
clpC1 4040471 c.234T>C synonymous_variant 0.33
clpC1 4040522 c.183T>C synonymous_variant 0.33
clpC1 4040528 c.177G>C synonymous_variant 0.33
clpC1 4040531 c.174T>C synonymous_variant 0.33
clpC1 4040534 c.171A>G synonymous_variant 0.33
clpC1 4040546 c.159G>C synonymous_variant 0.33
clpC1 4040551 c.154T>C synonymous_variant 0.4
embC 4240006 c.144A>C synonymous_variant 1.0
embC 4240819 c.957A>G synonymous_variant 0.22
embC 4240825 c.963G>A synonymous_variant 0.25
embC 4240831 c.969T>G synonymous_variant 0.25
embA 4244074 p.Ala281Val missense_variant 1.0
embA 4244276 c.1044A>C synonymous_variant 0.5
embA 4244284 p.Pro351Arg missense_variant 0.5
embA 4244298 p.Ser356Ala missense_variant 0.5
embA 4244309 c.1077C>G synonymous_variant 0.5
embA 4244312 c.1080T>G synonymous_variant 0.5
embA 4244315 c.1083G>C synonymous_variant 0.5
embA 4244324 c.1092T>G synonymous_variant 0.4
embA 4244327 c.1095T>C synonymous_variant 0.4
embA 4244337 p.Leu369Val missense_variant 0.4
embA 4244340 p.Ser370Ala missense_variant 0.4
embA 4244366 c.1134C>G synonymous_variant 0.33
embA 4244372 c.1140T>G synonymous_variant 0.29
embA 4244378 c.1146G>A synonymous_variant 0.29
embA 4244396 c.1164T>C synonymous_variant 0.29
embA 4244408 c.1176G>C synonymous_variant 0.25
embA 4245739 p.Arg836His missense_variant 0.75
embB 4247773 c.1260G>A synonymous_variant 0.29
embB 4247776 c.1263G>T synonymous_variant 0.25
embB 4247779 c.1266C>G synonymous_variant 0.25
embB 4247785 c.1272G>C synonymous_variant 0.25
embB 4247800 c.1287A>C synonymous_variant 0.2
embB 4247806 c.1293G>C synonymous_variant 0.2
embB 4248157 c.1644A>G synonymous_variant 0.25
embB 4248265 c.1752C>T synonymous_variant 0.18
embB 4248266 c.1753C>T synonymous_variant 0.18
embB 4248277 c.1764G>C synonymous_variant 0.17
ethA 4326731 p.Ala248Gly missense_variant 1.0
ethR 4327623 c.75_76insC frameshift_variant 1.0