TB-Profiler result

Run: SRR13861733
Summary

Run ID: SRR13861733

Sample name:

Date: 03-04-2023 09:39:10

Number of reads: 3389181

Percentage reads mapped: 56.54

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5922 p.Glu228Gly missense_variant 1.0
gyrB 7242 p.Lys668Thr missense_variant 1.0
ccsA 620360 p.Tyr157Ser missense_variant 0.99
rpoB 761356 c.1550_1551insA frameshift_variant 1.0
rpoC 763347 c.-23C>G upstream_gene_variant 1.0
rpoC 766025 p.Val886Met missense_variant 1.0
mmpL5 776145 p.Ala779Gly missense_variant 1.0
mmpL5 776954 p.Lys509Asn missense_variant 1.0
rplC 801231 c.423C>A synonymous_variant 1.0
atpE 1460916 c.-129G>A upstream_gene_variant 1.0
rrl 1476201 n.2544C>G non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.17
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.24
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.24
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.25
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.26
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.32
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.31
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.3
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.3
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.3
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.3
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.3
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.31
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.31
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.3
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.3
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.31
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.31
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.3
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.29
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.12
katG 2155137 c.975G>C synonymous_variant 1.0
PPE35 2168892 p.Thr574Lys missense_variant 1.0
Rv1979c 2222852 p.Ala105Thr missense_variant 1.0
ribD 2987259 p.Leu141Val missense_variant 1.0
Rv2752c 3065161 p.Asn344Thr missense_variant 1.0
Rv2752c 3065830 p.Ile121Thr missense_variant 1.0
Rv2752c 3067100 c.-909G>A upstream_gene_variant 1.0
fbiD 3339117 c.-1C>T upstream_gene_variant 1.0
Rv3083 3448661 p.Val53Ala missense_variant 1.0
Rv3236c 3612041 p.Val359Glu missense_variant 1.0
fbiA 3640418 c.-125C>A upstream_gene_variant 1.0
rpoA 3877877 p.Ala211Ser missense_variant 1.0
clpC1 4039250 c.1455C>G synonymous_variant 1.0
embC 4242113 c.2251C>T synonymous_variant 1.0
embB 4246367 c.-147C>T upstream_gene_variant 1.0
whiB6 4338567 c.-46C>T upstream_gene_variant 1.0
gid 4408302 c.-101delC upstream_gene_variant 1.0