TB-Profiler result

Run: SRR16100231
Summary

Run ID: SRR16100231

Sample name:

Date: 03-04-2023 16:18:35

Number of reads: 1180355

Percentage reads mapped: 62.16

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575177 c.-171G>C upstream_gene_variant 1.0
rpoB 761889 p.Val695Leu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801009 c.201A>G synonymous_variant 1.0
fbiC 1305494 c.2565_*55delGGCCTAGCCCCGGCGACGATGCCGGGTCGCGGGATGCGGCCCGTTGAGGAGCGGGGCAATCT frameshift_variant&stop_lost&splice_region_variant 0.43
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.14
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.19
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.19
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 0.2
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 0.2
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.2
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.2
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.21
rrs 1472266 n.421C>A non_coding_transcript_exon_variant 0.17
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.12
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 0.12
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.12
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.12
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.12
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.12
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.15
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.12
rrs 1472812 n.967A>C non_coding_transcript_exon_variant 0.12
rrs 1472887 n.1042G>C non_coding_transcript_exon_variant 0.13
rrl 1476336 n.2679C>G non_coding_transcript_exon_variant 0.17
rrl 1476356 n.2699C>G non_coding_transcript_exon_variant 0.18
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 0.17
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.24
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.34
rrl 1476384 n.2727G>C non_coding_transcript_exon_variant 0.33
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.32
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.32
rrl 1476428 n.2771C>A non_coding_transcript_exon_variant 0.38
rrl 1476443 n.2786G>C non_coding_transcript_exon_variant 0.35
rrl 1476455 n.2798C>G non_coding_transcript_exon_variant 0.36
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.37
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.37
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.37
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.36
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.28
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.17
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.13
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.12
rrl 1476521 n.2864C>T non_coding_transcript_exon_variant 0.12
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.12
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.12
rrl 1476535 n.2879_2880delGA non_coding_transcript_exon_variant 0.12
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.12
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.12
rrl 1476541 n.2885_2886insTT non_coding_transcript_exon_variant 0.12
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.11
rrl 1476569 n.2912G>A non_coding_transcript_exon_variant 0.11
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.11
rrl 1476584 n.2927C>G non_coding_transcript_exon_variant 0.1
rrl 1476586 n.2929C>G non_coding_transcript_exon_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223214 c.-50A>C upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860238 p.Arg61Gly missense_variant 1.0
Rv2752c 3065517 c.675C>T synonymous_variant 1.0
fprA 3474299 p.Asp98Gly missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4328317 c.-844C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407794 p.Arg137Trp missense_variant 0.98
fbiC 1305494 c.2565_*56delCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN frameshift_variant&stop_lost&splice_region_variant 1.0