TB-Profiler result

Run: SRR1735641
Summary

Run ID: SRR1735641

Sample name:

Date: 27-03-2023 14:43:07

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage2.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.99
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575907 p.Ala187Val missense_variant 0.98
ccsA 620625 p.Ile245Met missense_variant 0.98
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406760 c.580_581insC frameshift_variant 0.98
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.11
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.11
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.1
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.11
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.17
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.17
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.14
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.13
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.13
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.25
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.22
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.22
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.22
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.22
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.22
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.25
rrl 1474584 n.927C>T non_coding_transcript_exon_variant 0.25
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.17
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.18
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.18
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.22
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.36
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.36
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.18
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.18
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.23
rrl 1474673 n.1016T>G non_coding_transcript_exon_variant 0.15
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.38
rrl 1474694 n.1037C>T non_coding_transcript_exon_variant 0.27
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.25
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.15
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.31
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.2
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.23
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.46
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.5
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.5
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.36
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.27
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.3
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.33
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.2
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.2
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.2
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.2
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.2
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.22
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.2
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.18
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.27
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.18
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.36
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.23
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.21
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.21
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.21
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.2
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.18
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.18
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.18
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.18
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.18
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.18
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.19
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.32
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.29
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.27
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.14
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.23
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.24
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.16
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.22
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.17
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.22
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.33
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.29
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.18
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.36
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.16
rpsA 1834177 c.636A>C synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746606 c.993C>T synonymous_variant 0.11
ald 3086747 c.-73A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 0.97
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0