TB-Profiler result

Run: SRR2101671
Summary

Run ID: SRR2101671

Sample name:

Date: 03-04-2023 23:51:00

Number of reads: 446887

Percentage reads mapped: 97.65

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6363 p.Leu375Ser missense_variant 0.1
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 763481 p.Thr38Ala missense_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801124 p.Phe106Ile missense_variant 0.15
embR 1417347 c.1A>G start_lost 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473744 n.87T>C non_coding_transcript_exon_variant 0.13
rrl 1474112 n.458delC non_coding_transcript_exon_variant 0.13
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.1
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.19
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.19
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.19
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.18
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.18
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.18
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.18
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.17
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.17
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.17
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.18
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.18
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.18
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.2
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.22
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.26
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.33
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.33
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.34
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.34
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.34
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.34
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.36
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.35
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.34
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.24
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.24
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.24
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.23
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.23
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.23
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.23
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.23
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.23
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.23
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.23
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.22
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.17
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 0.17
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.14
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.13
rrl 1476789 n.3133delA non_coding_transcript_exon_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102147 p.Arg299Leu missense_variant 0.11
katG 2155429 p.Ile228Thr missense_variant 0.11
PPE35 2167657 p.Thr986Ala missense_variant 1.0
PPE35 2170462 p.Gly51Arg missense_variant 0.15
Rv1979c 2222999 p.Ile56Val missense_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2986912 p.Asp25Gly missense_variant 0.13
thyA 3074317 p.Phe52Ser missense_variant 0.11
fbiD 3339244 p.Leu43Phe missense_variant 0.1
fbiD 3339720 c.607delG frameshift_variant 0.12
fbiA 3640814 p.Glu91Val missense_variant 0.11
fbiB 3642014 p.Gln160His missense_variant 0.12
fbiB 3642394 p.Pro287Gln missense_variant 0.15
alr 3840400 p.Ile341Val missense_variant 0.11
alr 3840807 p.Asp205Gly missense_variant 1.0
embC 4242177 p.Pro772Gln missense_variant 0.11
embB 4247458 p.Tyr315* stop_gained 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0