TB-Profiler result

Run: SRR21700837
Summary

Run ID: SRR21700837

Sample name:

Date: 12-03-2024 18:46:26

Number of reads: 7737605

Percentage reads mapped: 99.97

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576179 p.Lys278Gln missense_variant 1.0
Rv1258c 1406686 p.Val219Ile missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
Rv3083 3449234 p.Arg244His missense_variant 0.47
rpoA 3878614 c.-107A>C upstream_gene_variant 0.12
rpoA 3878619 c.-112A>C upstream_gene_variant 0.15
embB 4247028 p.Leu172Arg missense_variant 0.11
ubiA 4269190 p.Ser215Asn missense_variant 1.0
ethA 4326842 p.Tyr211Cys missense_variant 1.0