TB-Profiler result

Run: SRR21732809

Summary

Run ID: SRR21732809

Sample name:

Date: 14-01-2024 16:04:55

Number of reads: 8544166

Percentage reads mapped: 99.63

Strain: lineage4

Drug-resistance: Sensitive


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576456 p.Val370Gly missense_variant 0.33
mshA 576651 p.Asp435Ala missense_variant 0.29
mshA 576657 p.Leu437Arg missense_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416436 p.Gln304His missense_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674999 c.798C>G synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154980 c.1132C>T synonymous_variant 1.0
PPE35 2169122 c.1491C>G synonymous_variant 0.98
PPE35 2169125 p.Val496Ile missense_variant 1.0
PPE35 2169131 c.1482C>T synonymous_variant 1.0
PPE35 2169134 c.1479G>A synonymous_variant 1.0
PPE35 2169141 p.Thr491Met missense_variant 1.0
PPE35 2169144 p.Val490Ala missense_variant 0.99
PPE35 2169149 c.1464G>A synonymous_variant 1.0
PPE35 2170811 c.-199C>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714450 p.Trp295Arg missense_variant 1.0
Rv2752c 3066064 p.Ile43Ser missense_variant 1.0
Rv3083 3449145 c.642G>A synonymous_variant 1.0
alr 3840794 c.627T>C synonymous_variant 1.0
panD 4044406 c.-125C>G upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245835 p.Leu868Arg missense_variant 0.15
aftB 4268076 p.Met254Ala missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0