TB-Profiler result

Run: SRR26159053
Summary

Run ID: SRR26159053

Sample name:

Date: 16-03-2024 13:32:36

Number of reads: 73966

Percentage reads mapped: 99.74

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.15
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.13
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.17
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.16
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.17
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.19
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.21
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.27
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.31
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.31
rrl 1476393 n.2736C>T non_coding_transcript_exon_variant 0.23
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.62
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.62
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.62
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.68
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.71
tlyA 1917972 c.33A>G synonymous_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 0.99