TB-Profiler result

Run: SRR4033580
Summary

Run ID: SRR4033580

Sample name:

Date: 04-04-2023 06:11:37

Number of reads: 1246815

Percentage reads mapped: 99.42

Strain: lineage4.1.2

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 0.99
lineage4.1.2 Euro-American T;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7323 p.Pro8Ala missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 0.96
rpoB 761165 c.1362delC frameshift_variant 0.11
rpoC 763416 p.Thr16Ile missense_variant 0.12
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776659 p.Asp608Asn missense_variant 1.0
mmpL5 777709 p.Leu258Phe missense_variant 0.13
mmpR5 779358 p.Arg123Ser missense_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416459 p.Ser297Pro missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168501 p.Phe704Leu missense_variant 0.96
PPE35 2169320 p.Leu431Phe missense_variant 0.36
Rv1979c 2223253 c.-89C>T upstream_gene_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2517965 c.-150C>G upstream_gene_variant 0.12
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
folC 2746775 p.Gln275Arg missense_variant 0.1
thyA 3073806 c.666C>G synonymous_variant 0.31
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449226 c.726delT frameshift_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3641969 c.435C>T synonymous_variant 0.17
fbiB 3642730 p.Gly399Asp missense_variant 0.11
rpoA 3878381 c.127C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243290 p.Ser20Ala missense_variant 1.0
embB 4246825 c.312G>A synonymous_variant 0.12
embB 4246886 p.Val125Ile missense_variant 0.12
embB 4247121 p.Ser203Leu missense_variant 1.0
embB 4247677 c.1164C>T synonymous_variant 0.13
embB 4247975 p.Val488Ile missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408397 c.-195A>G upstream_gene_variant 1.0