Run ID: SRR5818629
Sample name:
Date: 21-10-2023 05:04:43
Number of reads: 2743980
Percentage reads mapped: 98.03
Strain: lineage4.6.5
Drug-resistance: Other
| Drug | Resistance | Supporting mutations |
|---|---|---|
| Rifampicin | ||
| Isoniazid | ||
| Ethambutol | ||
| Pyrazinamide | ||
| Streptomycin | ||
| Fluoroquinolones | ||
| Moxifloxacin | ||
| Ofloxacin | ||
| Levofloxacin | ||
| Ciprofloxacin | ||
| Aminoglycosides | ||
| Amikacin | ||
| Capreomycin | R | tlyA p.Asn236Lys (0.99) |
| Kanamycin | ||
| Cycloserine | ||
| Ethionamide | ||
| Clofazimine | ||
| Para-aminosalicylic_acid | ||
| Delamanid | ||
| Bedaquiline | ||
| Linezolid |
| Lineage | Family | Main Spoligotype | RDs | Frequency |
|---|---|---|---|---|
| lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
| lineage4.6 | Euro-American | T;LAM | None | 1.0 |
| lineage4.6.5 | Euro-American | T;LAM | None | 1.0 |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
|---|---|---|---|---|---|
| tlyA | 1918647 | p.Asn236Lys | missense_variant | 0.99 | capreomycin |
| Gene | Chromosome position | Mutation | Type | Estimated fraction |
|---|---|---|---|---|
| gyrB | 5489 | p.Ile84Val | missense_variant | 1.0 |
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
| fgd1 | 490756 | c.-27T>G | upstream_gene_variant | 1.0 |
| mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
| mmpL5 | 777974 | c.507C>T | synonymous_variant | 1.0 |
| rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
| rrl | 1476425 | n.2768G>T | non_coding_transcript_exon_variant | 0.14 |
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.18 |
| rrl | 1476429 | n.2772A>C | non_coding_transcript_exon_variant | 0.15 |
| rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.17 |
| rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.12 |
| tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
| katG | 2155560 | c.552C>T | synonymous_variant | 1.0 |
| Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
| folC | 2746995 | p.Val202Ile | missense_variant | 1.0 |
| fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
| fbiA | 3640346 | c.-196delA | upstream_gene_variant | 1.0 |
| clpC1 | 4038332 | c.2373C>T | synonymous_variant | 0.99 |
| embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
| whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
