TB-Profiler result

Run: SRR6046807
Summary

Run ID: SRR6046807

Sample name:

Date: 04-04-2023 12:23:44

Number of reads: 117454

Percentage reads mapped: 6.31

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5497 c.258C>G synonymous_variant 0.5
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9385 p.Arg695Leu missense_variant 0.67
rpoB 759921 p.Arg39Gly missense_variant 0.5
rpoB 761875 p.Val690Asp missense_variant 0.25
rpoB 762353 c.2547C>T synonymous_variant 0.29
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 764803 c.1434C>T synonymous_variant 0.67
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777015 p.Gly489Asp missense_variant 0.25
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781682 c.123T>C synonymous_variant 0.22
rpsL 781721 c.162C>T synonymous_variant 0.2
rpsL 781728 c.169T>C synonymous_variant 0.18
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.67
rpsA 1834052 p.Ala171Thr missense_variant 0.29
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170611 c.2T>A start_lost 0.17
Rv1979c 2221955 p.His404Tyr missense_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
kasA 2518161 p.Val16Gly missense_variant 0.67
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4243537 p.Lys102Arg missense_variant 0.33
ethA 4327455 p.Val7Ile missense_variant 0.4
ethA 4327544 c.-71G>A upstream_gene_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0