TB-Profiler result

Run: ERR11044905
Summary

Run ID: ERR11044905

Sample name:

Date: 31-03-2023 12:02:33

Number of reads: 814191

Percentage reads mapped: 99.35

Strain: lineage3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9647 c.2346C>G synonymous_variant 0.23
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.22
mshA 576113 p.Arg256Gly missense_variant 0.22
mshA 576357 p.Ala337Val missense_variant 0.12
mshA 576453 p.Val369Gly missense_variant 0.33
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 764367 p.Gly333Ala missense_variant 0.25
rpoC 764537 p.Pro390Ala missense_variant 0.23
rpoC 766582 c.3213C>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777599 c.882C>T synonymous_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1407271 p.Gly24Cys missense_variant 1.0
embR 1417023 p.Thr109Pro missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.15
inhA 1673661 c.-541G>C upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.31
ribD 2987506 p.Leu223Arg missense_variant 0.19
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087816 p.Cys333Gly missense_variant 0.12
fbiD 3339734 p.Ala206Val missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
alr 3840467 c.954G>T synonymous_variant 0.12
alr 3841473 c.-53G>A upstream_gene_variant 1.0
embC 4240318 p.Cys152* stop_gained 0.13
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246727 p.Ile72Phe missense_variant 0.12
embB 4247016 p.Ser168Trp missense_variant 0.23
embB 4247020 c.507C>G synonymous_variant 0.22
embB 4248328 c.1815G>C synonymous_variant 0.2
whiB6 4338205 p.Val106Gly missense_variant 0.44
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0