TB-Profiler result

Run: ERR11050068
Summary

Run ID: ERR11050068

Sample name:

Date: 02-04-2023 10:17:09

Number of reads: 4492698

Percentage reads mapped: 99.44

Strain: lineage3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9647 c.2346C>G synonymous_variant 0.2
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 576113 p.Arg256Gly missense_variant 0.19
mshA 576116 p.Ala257Pro missense_variant 0.19
mshA 576456 p.Val370Gly missense_variant 0.33
mshA 576606 p.Ala420Gly missense_variant 0.26
mshA 576609 p.Ala421Gly missense_variant 0.27
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 761161 p.Leu452Arg missense_variant 0.19
rpoC 762434 c.-936T>G upstream_gene_variant 0.99
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 764367 p.Gly333Ala missense_variant 0.25
rpoC 764537 p.Pro390Ala missense_variant 0.12
rpoC 766582 c.3213C>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.25
mmpR5 779115 p.Trp42Cys missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.36
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170047 p.Leu189Pro missense_variant 0.14
PPE35 2170069 p.Pro182Ala missense_variant 0.21
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.31
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.2
Rv2752c 3064823 p.Val457Leu missense_variant 0.19
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339751 p.Ala212Pro missense_variant 0.63
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474213 p.Lys69Asn missense_variant 0.14
whiB7 3568428 c.252A>G synonymous_variant 0.57
alr 3841473 c.-53G>A upstream_gene_variant 1.0
rpoA 3878641 c.-134C>G upstream_gene_variant 0.8
clpC1 4039702 p.Asp335His missense_variant 0.17
clpC1 4040550 p.Leu52Trp missense_variant 0.19
embC 4239851 c.-12G>C upstream_gene_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.29
embC 4242075 p.Arg738Gln missense_variant 0.98
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.42
embB 4248328 c.1815G>C synonymous_variant 0.19
aftB 4267400 c.1437G>C synonymous_variant 0.17
aftB 4267902 p.Val312Gly missense_variant 0.23
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0