TB-Profiler result

Run: ERR11067893
Summary

Run ID: ERR11067893

Sample name:

Date: 05-04-2023 14:06:21

Number of reads: 5690163

Percentage reads mapped: 99.43

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490899 c.117C>T synonymous_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759906 p.Ser34Ala missense_variant 1.0
rpoB 760008 p.Ala68Thr missense_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.99
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
fbiC 1305024 c.2094C>T synonymous_variant 1.0
Rv1258c 1406615 p.Met242Ile missense_variant 0.99
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475529 n.1872A>T non_coding_transcript_exon_variant 1.0
tlyA 1917835 c.-105A>G upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156558 c.-447G>A upstream_gene_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168803 p.Gly604Arg missense_variant 1.0
Rv1979c 2222090 c.1075T>C synonymous_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
pepQ 2859871 p.His183Arg missense_variant 1.0
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474019 p.Tyr5His missense_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
whiB7 3568428 c.252A>C synonymous_variant 0.28
fbiB 3642538 p.Val335Ala missense_variant 1.0
rpoA 3877535 p.Val325Phe missense_variant 1.0
rpoA 3878641 c.-134C>G upstream_gene_variant 0.4
embC 4240498 c.636G>A synonymous_variant 1.0
embC 4240518 p.Asp219Ala missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244014 p.Leu261Ser missense_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embB 4246864 c.351C>T synonymous_variant 1.0
embB 4247024 p.Pro171Ala missense_variant 0.19
embB 4247646 p.Glu378Ala missense_variant 1.0
aftB 4268732 c.105G>C synonymous_variant 1.0
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4408268 c.-66G>T upstream_gene_variant 1.0