Run ID: ERR2510489
Sample name:
Date: 31-03-2023 18:46:23
Number of reads: 1466133
Percentage reads mapped: 99.68
Strain: lineage4.6.5
Drug-resistance: RR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.6 | Euro-American | T;LAM | None | 1.0 |
lineage4.6.5 | Euro-American | T;LAM | None | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rpoB | 761155 | p.Ser450Leu | missense_variant | 1.0 | rifampicin |
tlyA | 1918647 | p.Asn236Lys | missense_variant | 1.0 | capreomycin |
pncA | 2288864 | c.376_377dupGA | frameshift_variant | 0.32 | pyrazinamide |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
mmpL5 | 777974 | c.507C>T | synonymous_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrs | 1471690 | n.-156G>A | upstream_gene_variant | 0.12 |
rrs | 1472015 | n.170A>T | non_coding_transcript_exon_variant | 0.18 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
pncA | 2289102 | p.Thr47Ile | missense_variant | 0.66 |
folC | 2746995 | p.Val202Ile | missense_variant | 1.0 |
ald | 3087281 | c.462G>A | synonymous_variant | 1.0 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
whiB7 | 3568418 | c.250_261delGGACGTCCGCGC | conservative_inframe_deletion | 1.0 |
clpC1 | 4038332 | c.2373C>T | synonymous_variant | 1.0 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
ubiA | 4269122 | p.Phe238Ile | missense_variant | 1.0 |
ethA | 4326174 | p.Phe434Ile | missense_variant | 0.11 |
whiB6 | 4338535 | c.-14C>T | upstream_gene_variant | 1.0 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |